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1-(4-Phenylpiperazin-1-yl)-2-(1H-pyrazol-1-yl)ethanones as novel CCR1 antagonists.
Pennell AM, Aggen JB, Sen S, Chen W, Xu Y, Sullivan E, Li L, Greenman K, Charvat T, Hansen D, Dairaghi DJ, Wright JJ, Zhang P. Pennell AM, et al. Among authors: aggen jb. Bioorg Med Chem Lett. 2013 Mar 1;23(5):1228-31. doi: 10.1016/j.bmcl.2013.01.005. Epub 2013 Jan 11. Bioorg Med Chem Lett. 2013. PMID: 23374868
Compound design guidelines for evading the efflux and permeation barriers of Escherichia coli with the oxazolidinone class of antibacterials: Test case for a general approach to improving whole cell Gram-negative activity.
Spaulding A, Takrouri K, Mahalingam P, Cleary DC, Cooper HD, Zucchi P, Tear W, Koleva B, Beuning PJ, Hirsch EB, Aggen JB. Spaulding A, et al. Among authors: aggen jb. Bioorg Med Chem Lett. 2017 Dec 1;27(23):5310-5321. doi: 10.1016/j.bmcl.2017.10.018. Epub 2017 Oct 16. Bioorg Med Chem Lett. 2017. PMID: 29102393
A central strategy for converting natural products into fluorescent probes.
Alexander MD, Burkart MD, Leonard MS, Portonovo P, Liang B, Ding X, Joullié MM, Gulledge BM, Aggen JB, Chamberlin AR, Sandler J, Fenical W, Cui J, Gharpure SJ, Polosukhin A, Zhang HR, Evans PA, Richardson AD, Harper MK, Ireland CM, Vong BG, Brady TP, Theodorakis EA, La Clair JJ. Alexander MD, et al. Among authors: aggen jb. Chembiochem. 2006 Mar;7(3):409-16. doi: 10.1002/cbic.200500466. Chembiochem. 2006. PMID: 16432909 No abstract available.
Congener-independent immunoassay for microcystins and nodularins.
Fischer WJ, Garthwaite I, Miles CO, Ross KM, Aggen JB, Chamberlin AR, Towers NR, Dietrich DR. Fischer WJ, et al. Among authors: aggen jb. Environ Sci Technol. 2001 Dec 15;35(24):4849-56. doi: 10.1021/es011182f. Environ Sci Technol. 2001. PMID: 11775161
A multivalent approach to drug discovery for novel antibiotics.
Long DD, Aggen JB, Christensen BG, Judice JK, Hegde SS, Kaniga K, Krause KM, Linsell MS, Moran EJ, Pace JL. Long DD, et al. Among authors: aggen jb. J Antibiot (Tokyo). 2008 Oct;61(10):595-602. doi: 10.1038/ja.2008.79. J Antibiot (Tokyo). 2008. PMID: 19168973
Exploring the positional attachment of glycopeptide/beta-lactam heterodimers.
Long DD, Aggen JB, Chinn J, Choi SK, Christensen BG, Fatheree PR, Green D, Hegde SS, Judice JK, Kaniga K, Krause KM, Leadbetter M, Linsell MS, Marquess DG, Moran EJ, Nodwell MB, Pace JL, Trapp SG, Turner SD. Long DD, et al. Among authors: aggen jb. J Antibiot (Tokyo). 2008 Oct;61(10):603-14. doi: 10.1038/ja.2008.80. J Antibiot (Tokyo). 2008. PMID: 19168974
23 results