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A predictor model of treatment resistance in schizophrenia using data from electronic health records.
Kadra-Scalzo G, Fonseca de Freitas D, Agbedjro D, Francis E, Ridler I, Pritchard M, Shetty H, Segev A, Casetta C, Smart SE, Morris A, Downs J, Christensen SR, Bak N, Kinon BJ, Stahl D, Hayes RD, MacCabe JH. Kadra-Scalzo G, et al. Among authors: agbedjro d. PLoS One. 2022 Sep 19;17(9):e0274864. doi: 10.1371/journal.pone.0274864. eCollection 2022. PLoS One. 2022. PMID: 36121864 Free PMC article.
Predicting onset of early- and late-treatment resistance in first-episode schizophrenia patients using advanced shrinkage statistical methods in a small sample.
Ajnakina O, Agbedjro D, Lally J, Forti MD, Trotta A, Mondelli V, Pariante C, Dazzan P, Gaughran F, Fisher HL, David A, Murray RM, Stahl D. Ajnakina O, et al. Among authors: agbedjro d. Psychiatry Res. 2020 Dec;294:113527. doi: 10.1016/j.psychres.2020.113527. Epub 2020 Oct 21. Psychiatry Res. 2020. PMID: 33126015
Development and validation of prediction model to estimate 10-year risk of all-cause mortality using modern statistical learning methods: a large population-based cohort study and external validation.
Ajnakina O, Agbedjro D, McCammon R, Faul J, Murray RM, Stahl D, Steptoe A. Ajnakina O, et al. Among authors: agbedjro d. BMC Med Res Methodol. 2021 Jan 6;21(1):8. doi: 10.1186/s12874-020-01204-7. BMC Med Res Methodol. 2021. PMID: 33407175 Free PMC article.
Interaction Testing and Polygenic Risk Scoring to Estimate the Association of Common Genetic Variants With Treatment Resistance in Schizophrenia.
Pardiñas AF, Smart SE, Willcocks IR, Holmans PA, Dennison CA, Lynham AJ, Legge SE, Baune BT, Bigdeli TB, Cairns MJ, Corvin A, Fanous AH, Frank J, Kelly B, McQuillin A, Melle I, Mortensen PB, Mowry BJ, Pato CN, Periyasamy S, Rietschel M, Rujescu D, Simonsen C, St Clair D, Tooney P, Wu JQ, Andreassen OA, Kowalec K, Sullivan PF, Murray RM, Owen MJ, MacCabe JH, O'Donovan MC, Walters JTR; Genetics Workstream of the Schizophrenia Treatment Resistance and Therapeutic Advances (STRATA) Consortium and the Schizophrenia Working Group of the Psychiatric Genomics Consortium (PGC); Ajnakina O, Alameda L, Barnes TRE, Berardi D, Bonora E, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D'Andrea G, Demjaha A, Do KQ, Doody GA, Eap CB, Ferchiou A, Di Forti M, Guidi L, Homman L, Jenni R, Joyce EM, Kassoumeri L, Khadimallah I, Lastrina O, Muratori R, Noyan H, O'Neill FA, Pignon B, Restellini R, Richard JR, Schürhoff F, Španiel F, Szöke A, Tarricone I, Tortelli A, Üçok A, Vázquez-Bourgon J. Pardiñas AF, et al. JAMA Psychiatry. 2022 Mar 1;79(3):260-269. doi: 10.1001/jamapsychiatry.2021.3799. JAMA Psychiatry. 2022. PMID: 35019943 Free PMC article.
Using a statistical learning approach to identify sociodemographic and clinical predictors of response to clozapine.
Fonseca de Freitas D, Kadra-Scalzo G, Agbedjro D, Francis E, Ridler I, Pritchard M, Shetty H, Segev A, Casetta C, Smart SE, Downs J, Christensen SR, Bak N, Kinon BJ, Stahl D, MacCabe JH, Hayes RD. Fonseca de Freitas D, et al. Among authors: agbedjro d. J Psychopharmacol. 2022 Apr;36(4):498-506. doi: 10.1177/02698811221078746. Epub 2022 Feb 25. J Psychopharmacol. 2022. PMID: 35212240 Free PMC article.
Clinical predictors of antipsychotic treatment resistance: Development and internal validation of a prognostic prediction model by the STRATA-G consortium.
Smart SE, Agbedjro D, Pardiñas AF, Ajnakina O, Alameda L, Andreassen OA, Barnes TRE, Berardi D, Camporesi S, Cleusix M, Conus P, Crespo-Facorro B, D'Andrea G, Demjaha A, Di Forti M, Do K, Doody G, Eap CB, Ferchiou A, Guidi L, Homman L, Jenni R, Joyce E, Kassoumeri L, Lastrina O, Melle I, Morgan C, O'Neill FA, Pignon B, Restellini R, Richard JR, Simonsen C, Španiel F, Szöke A, Tarricone I, Tortelli A, Üçok A, Vázquez-Bourgon J, Murray RM, Walters JTR, Stahl D, MacCabe JH. Smart SE, et al. Among authors: agbedjro d. Schizophr Res. 2022 Dec;250:1-9. doi: 10.1016/j.schres.2022.09.009. Epub 2022 Oct 12. Schizophr Res. 2022. PMID: 36242784 Free PMC article.
Clinical correlates of early onset antipsychotic treatment resistance.
Fonseca de Freitas D, Agbedjro D, Kadra-Scalzo G, Francis E, Ridler I, Pritchard M, Shetty H, Segev A, Casetta C, Smart SE, Morris A, Downs J, Christensen SR, Bak N, Kinon BJ, Stahl D, Hayes RD, MacCabe JH. Fonseca de Freitas D, et al. Among authors: agbedjro d. J Psychopharmacol. 2022 Nov;36(11):1226-1233. doi: 10.1177/02698811221132537. Epub 2022 Oct 21. J Psychopharmacol. 2022. PMID: 36268751 Free PMC article.
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