Agarwal P - Search Results

1

Microenvironmental CXCL12 deletion enhances Flt3-ITD acute myeloid leukemia stem cell response to therapy by reducing p38 MAPK signaling.

Anderson NR, Sheth V, Li H, Harris MW, Qiu S, Crossman DK, Kumar H, Agarwal P, Nagasawa T, Paterson AJ, Welner RS, Bhatia R. Anderson NR, et al. Among authors: agarwal p. Leukemia. 2023 Mar;37(3):560-570. doi: 10.1038/s41375-022-01798-5. Epub 2022 Dec 22. Leukemia. 2023. PMID: 36550214 Free PMC article.

2

SIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells.

Li L, Osdal T, Ho Y, Chun S, McDonald T, Agarwal P, Lin A, Chu S, Qi J, Li L, Hsieh YT, Dos Santos C, Yuan H, Ha TQ, Popa M, Hovland R, Bruserud Ø, Gjertsen BT, Kuo YH, Chen W, Lain S, McCormack E, Bhatia R. Li L, et al. Among authors: agarwal p. Cell Stem Cell. 2014 Oct 2;15(4):431-446. doi: 10.1016/j.stem.2014.08.001. Cell Stem Cell. 2014. PMID: 25280219 Free PMC article.

3

Osteoblast ablation reduces normal long-term hematopoietic stem cell self-renewal but accelerates leukemia development.

Bowers M, Zhang B, Ho Y, Agarwal P, Chen CC, Bhatia R. Bowers M, et al. Among authors: agarwal p. Blood. 2015 Apr 23;125(17):2678-88. doi: 10.1182/blood-2014-06-582924. Epub 2015 Mar 5. Blood. 2015. PMID: 25742698 Free PMC article.

4

Influence of Bone Marrow Microenvironment on Leukemic Stem Cells: Breaking Up an Intimate Relationship.

Agarwal P, Bhatia R. Agarwal P, et al. Adv Cancer Res. 2015;127:227-52. doi: 10.1016/bs.acr.2015.04.007. Epub 2015 May 19. Adv Cancer Res. 2015. PMID: 26093902 Review.

5

Inhibition of interleukin-1 signaling enhances elimination of tyrosine kinase inhibitor-treated CML stem cells.

Zhang B, Chu S, Agarwal P, Campbell VL, Hopcroft L, Jørgensen HG, Lin A, Gaal K, Holyoake TL, Bhatia R. Zhang B, et al. Among authors: agarwal p. Blood. 2016 Dec 8;128(23):2671-2682. doi: 10.1182/blood-2015-11-679928. Epub 2016 Sep 12. Blood. 2016. PMID: 27621307 Free PMC article.

6

Enhanced targeting of CML stem and progenitor cells by inhibition of porcupine acyltransferase in combination with TKI.

Agarwal P, Zhang B, Ho Y, Cook A, Li L, Mikhail FM, Wang Y, McLaughlin ME, Bhatia R. Agarwal P, et al. Blood. 2017 Feb 23;129(8):1008-1020. doi: 10.1182/blood-2016-05-714089. Epub 2016 Dec 23. Blood. 2017. PMID: 28011678 Free PMC article.

7

Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.

Agarwal P, Isringhausen S, Li H, Paterson AJ, He J, Gomariz Á, Nagasawa T, Nombela-Arrieta C, Bhatia R. Agarwal P, et al. Cell Stem Cell. 2019 May 2;24(5):769-784.e6. doi: 10.1016/j.stem.2019.02.018. Epub 2019 Mar 21. Cell Stem Cell. 2019. PMID: 30905620 Free PMC article.

8

SIRT1 regulates metabolism and leukemogenic potential in CML stem cells.

Abraham A, Qiu S, Chacko BK, Li H, Paterson A, He J, Agarwal P, Shah M, Welner R, Darley-Usmar VM, Bhatia R. Abraham A, et al. Among authors: agarwal p. J Clin Invest. 2019 Jun 10;129(7):2685-2701. doi: 10.1172/JCI127080. eCollection 2019 Jun 10. J Clin Invest. 2019. PMID: 31180336 Free PMC article.

9

Mapping Distinct Bone Marrow Niche Populations and Their Differentiation Paths.

Wolock SL, Krishnan I, Tenen DE, Matkins V, Camacho V, Patel S, Agarwal P, Bhatia R, Tenen DG, Klein AM, Welner RS. Wolock SL, et al. Among authors: agarwal p. Cell Rep. 2019 Jul 9;28(2):302-311.e5. doi: 10.1016/j.celrep.2019.06.031. Cell Rep. 2019. PMID: 31291568 Free PMC article.

10

Mesenchymal Niche-Specific Expression of Cxcl12 Controls Quiescence of Treatment-Resistant Leukemia Stem Cells.

Agarwal P, Isringhausen S, Li H, Paterson AJ, He J, Gomariz Á, Nagasawa T, Nombela-Arrieta C, Bhatia R. Agarwal P, et al. Cell Stem Cell. 2020 Jan 2;26(1):123. doi: 10.1016/j.stem.2019.11.013. Cell Stem Cell. 2020. PMID: 31901250 Free PMC article. No abstract available.

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