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Tryptophan depletion results in tryptophan-to-phenylalanine substitutants.
Pataskar A, Champagne J, Nagel R, Kenski J, Laos M, Michaux J, Pak HS, Bleijerveld OB, Mordente K, Navarro JM, Blommaert N, Nielsen MM, Lovecchio D, Stone E, Georgiou G, de Gooijer MC, van Tellingen O, Altelaar M, Joosten RP, Perrakis A, Olweus J, Bassani-Sternberg M, Peeper DS, Agami R. Pataskar A, et al. Among authors: agami r. Nature. 2022 Mar;603(7902):721-727. doi: 10.1038/s41586-022-04499-2. Epub 2022 Mar 9. Nature. 2022. PMID: 35264796 Free PMC article.
RNA-binding protein Dnd1 inhibits microRNA access to target mRNA.
Kedde M, Strasser MJ, Boldajipour B, Oude Vrielink JA, Slanchev K, le Sage C, Nagel R, Voorhoeve PM, van Duijse J, Ørom UA, Lund AH, Perrakis A, Raz E, Agami R. Kedde M, et al. Among authors: agami r. Cell. 2007 Dec 28;131(7):1273-86. doi: 10.1016/j.cell.2007.11.034. Cell. 2007. PMID: 18155131 Free article.
Tumour-specific proline vulnerability uncovered by differential ribosome codon reading.
Loayza-Puch F, Rooijers K, Buil LC, Zijlstra J, Oude Vrielink JF, Lopes R, Ugalde AP, van Breugel P, Hofland I, Wesseling J, van Tellingen O, Bex A, Agami R. Loayza-Puch F, et al. Among authors: agami r. Nature. 2016 Feb 25;530(7591):490-4. doi: 10.1038/nature16982. Epub 2016 Feb 15. Nature. 2016. PMID: 26878238
SLC1A3 contributes to L-asparaginase resistance in solid tumors.
Sun J, Nagel R, Zaal EA, Ugalde AP, Han R, Proost N, Song JY, Pataskar A, Burylo A, Fu H, Poelarends GJ, van de Ven M, van Tellingen O, Berkers CR, Agami R. Sun J, et al. Among authors: agami r. EMBO J. 2019 Oct 4;38(21):e102147. doi: 10.15252/embj.2019102147. Epub 2019 Sep 16. EMBO J. 2019. PMID: 31523835 Free PMC article.
Anti-tumour immunity induces aberrant peptide presentation in melanoma.
Bartok O, Pataskar A, Nagel R, Laos M, Goldfarb E, Hayoun D, Levy R, Körner PR, Kreuger IZM, Champagne J, Zaal EA, Bleijerveld OB, Huang X, Kenski J, Wargo J, Brandis A, Levin Y, Mizrahi O, Alon M, Lebon S, Yang W, Nielsen MM, Stern-Ginossar N, Altelaar M, Berkers CR, Geiger T, Peeper DS, Olweus J, Samuels Y, Agami R. Bartok O, et al. Among authors: agami r. Nature. 2021 Feb;590(7845):332-337. doi: 10.1038/s41586-020-03054-1. Epub 2020 Dec 16. Nature. 2021. PMID: 33328638
A comprehensive enhancer screen identifies TRAM2 as a key and novel mediator of YAP oncogenesis.
Li L, Ugalde AP, Scheele CLGJ, Dieter SM, Nagel R, Ma J, Pataskar A, Korkmaz G, Elkon R, Chien MP, You L, Su PR, Bleijerveld OB, Altelaar M, Momchev L, Manber Z, Han R, van Breugel PC, Lopes R, Ten Dijke P, van Rheenen J, Agami R. Li L, et al. Among authors: agami r. Genome Biol. 2021 Jan 29;22(1):54. doi: 10.1186/s13059-021-02272-8. Genome Biol. 2021. PMID: 33514403 Free PMC article.
138 results