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Page 1
Spatial immune composition of tumor microenvironment in patients with pancreatic cancer.
Zwart ES, van Ee T, Affandi AJ, Boyd LNC, Rodriguez E, den Haan JMM, Farina A, van Grieken NCT, Meijer LL, van Kooyk Y, Mebius RE, Kazemier G. Zwart ES, et al. Among authors: affandi aj. Cancer Immunol Immunother. 2023 Dec;72(12):4385-4397. doi: 10.1007/s00262-023-03573-6. Epub 2023 Nov 8. Cancer Immunol Immunother. 2023. PMID: 37938368 Free PMC article.
Platelets interact with CD169+ macrophages and cDC1 and enhance liposome-induced CD8+ T cell responses.
Grabowska J, Léopold V, Olesek K, Nijen Twilhaar MK, Affandi AJ, Brouwer MC, Jongerius I, Verschoor A, van Kooten C, van Kooyk Y, Storm G, van 't Veer C, den Haan JMM. Grabowska J, et al. Among authors: affandi aj. Front Immunol. 2023 Nov 20;14:1290272. doi: 10.3389/fimmu.2023.1290272. eCollection 2023. Front Immunol. 2023. PMID: 38054006 Free PMC article.
Impaired LAIR-1-mediated immune control due to collagen degradation in fibrosis.
Carvalheiro T, Marut W, Pascoal Ramos MI, García S, Fleury D, Affandi AJ, Meijers AS, Giovannone B, Tieland RG, Elshof E, Ottria A, Cossu M, Meizlish ML, Veenendaal T, Ramanujam M, Moreno-García ME, Klumperman J, Liv N, Radstake TRDJ, Meyaard L. Carvalheiro T, et al. Among authors: affandi aj. J Autoimmun. 2024 May 1;146:103219. doi: 10.1016/j.jaut.2024.103219. Online ahead of print. J Autoimmun. 2024. PMID: 38696927 Free article.
Nuclear Receptor Subfamily 4A Signaling as a Key Disease Pathway of CD1c+ Dendritic Cell Dysregulation in Systemic Sclerosis.
Servaas NH, Hiddingh S, Chouri E, Wichers CGK, Affandi AJ, Ottria A, Bekker CPJ, Cossu M, Silva-Cardoso SC, van der Kroef M, Hinrichs AC, Carvalheiro T, Vazirpanah N, Beretta L, Rossato M, Bonte-Mineur F, Radstake TRDJ, Kuiper JJW, Boes M, Pandit A. Servaas NH, et al. Among authors: affandi aj. Arthritis Rheumatol. 2023 Feb;75(2):279-292. doi: 10.1002/art.42319. Epub 2022 Dec 8. Arthritis Rheumatol. 2023. PMID: 36482877 Free PMC article.
Incorporation of Toll-Like Receptor Ligands and Inflammasome Stimuli in GM3 Liposomes to Induce Dendritic Cell Maturation and T Cell Responses.
Nijen Twilhaar MK, Czentner L, Bouma RG, Olesek K, Grabowska J, Wang AZ, Affandi AJ, Belt SC, Kalay H, van Nostrum CF, van Kooyk Y, Storm G, den Haan JMM. Nijen Twilhaar MK, et al. Among authors: affandi aj. Front Immunol. 2022 Feb 18;13:842241. doi: 10.3389/fimmu.2022.842241. eCollection 2022. Front Immunol. 2022. PMID: 35251040 Free PMC article.
CXCL4 drives fibrosis by promoting several key cellular and molecular processes.
Affandi AJ, Carvalheiro T, Ottria A, de Haan JJ, Brans MAD, Brandt MM, Tieland RG, Lopes AP, Fernández BM, Bekker CPJ, van der Linden M, Zimmermann M, Giovannone B, Wichers CGK, Garcia S, de Kok M, Stifano G, Xu YJ, Kowalska MA, Waasdorp M, Cheng C, Gibbs S, de Jager SCA, van Roon JAG, Radstake TRDJ, Marut W. Affandi AJ, et al. Cell Rep. 2022 Jan 4;38(1):110189. doi: 10.1016/j.celrep.2021.110189. Cell Rep. 2022. PMID: 34986347 Free article.
Hypoxia and TLR9 activation drive CXCL4 production in systemic sclerosis plasmacytoid dendritic cells via mtROS and HIF-2α.
Ottria A, Zimmermann M, Paardekooper LM, Carvalheiro T, Vazirpanah N, Silva-Cardoso S, Affandi AJ, Chouri E, V D Kroef M, Tieland RG, Bekker CPJ, Wichers CGK, Rossato M, Mocholi-Gimeno E, Tekstra J, Ton E, van Laar JM, Cossu M, Beretta L, Garcia Perez S, Pandit A, Bonte-Mineur F, Reedquist KA, van den Bogaart G, Radstake TRDJ, Marut W. Ottria A, et al. Among authors: affandi aj. Rheumatology (Oxford). 2022 May 30;61(6):2682-2693. doi: 10.1093/rheumatology/keab532. Rheumatology (Oxford). 2022. PMID: 34559222
CD169 Defines Activated CD14+ Monocytes With Enhanced CD8+ T Cell Activation Capacity.
Affandi AJ, Olesek K, Grabowska J, Nijen Twilhaar MK, Rodríguez E, Saris A, Zwart ES, Nossent EJ, Kalay H, de Kok M, Kazemier G, Stöckl J, van den Eertwegh AJM, de Gruijl TD, Garcia-Vallejo JJ, Storm G, van Kooyk Y, den Haan JMM. Affandi AJ, et al. Front Immunol. 2021 Jul 28;12:697840. doi: 10.3389/fimmu.2021.697840. eCollection 2021. Front Immunol. 2021. PMID: 34394090 Free PMC article.
34 results