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Internalization and trafficking of CSPG-bound recombinant VAR2CSA lectins in cancer cells.
Wang CK, Nelepcu I, Hui D, Oo HZ, Truong S, Zhao S, Tahiry Z, Esfandnia S, Ghaidi F, Adomat H, Dagil R, Gustavsson T, Choudhary S, Salanti A, Sorensen PH, Al Nakouzi N, Daugaard M. Wang CK, et al. Among authors: adomat h. Sci Rep. 2022 Feb 23;12(1):3075. doi: 10.1038/s41598-022-07025-6. Sci Rep. 2022. PMID: 35197518 Free PMC article.
Targeting Binding Function-3 of the Androgen Receptor Blocks Its Co-Chaperone Interactions, Nuclear Translocation, and Activation.
Lallous N, Leblanc E, Munuganti RS, Hassona MD, Nakouzi NA, Awrey S, Morin H, Roshan-Moniri M, Singh K, Lawn S, Yamazaki T, Adomat HH, Andre C, Daugaard M, Young RN, Guns ES, Rennie PS, Cherkasov A. Lallous N, et al. Among authors: adomat hh. Mol Cancer Ther. 2016 Dec;15(12):2936-2945. doi: 10.1158/1535-7163.MCT-16-0354. Epub 2016 Oct 7. Mol Cancer Ther. 2016. PMID: 27765852 Free PMC article.
BAP1 haploinsufficiency predicts a distinct immunogenic class of malignant peritoneal mesothelioma.
Shrestha R, Nabavi N, Lin YY, Mo F, Anderson S, Volik S, Adomat HH, Lin D, Xue H, Dong X, Shukin R, Bell RH, McConeghy B, Haegert A, Brahmbhatt S, Li E, Oo HZ, Hurtado-Coll A, Fazli L, Zhou J, McConnell Y, McCart A, Lowy A, Morin GB, Chen T, Daugaard M, Sahinalp SC, Hach F, Le Bihan S, Gleave ME, Wang Y, Churg A, Collins CC. Shrestha R, et al. Among authors: adomat hh. Genome Med. 2019 Feb 18;11(1):8. doi: 10.1186/s13073-019-0620-3. Genome Med. 2019. PMID: 30777124 Free PMC article.
Androgen receptor (AR) antagonism triggers acute succinate-mediated adaptive responses to reactivate AR signaling.
Saxena N, Beraldi E, Fazli L, Somasekharan SP, Adomat H, Zhang F, Molokwu C, Gleave A, Nappi L, Nguyen K, Brar P, Nikesitch N, Wang Y, Collins C, Sorensen PH, Gleave M. Saxena N, et al. Among authors: adomat h. EMBO Mol Med. 2021 May 7;13(5):e13427. doi: 10.15252/emmm.202013427. Epub 2021 Mar 11. EMBO Mol Med. 2021. PMID: 33709547 Free PMC article.
Oncofetal Chondroitin Sulfate Is a Highly Expressed Therapeutic Target in Non-Small Cell Lung Cancer.
Oo HZ, Lohinai Z, Khazamipour N, Lo J, Kumar G, Pihl J, Adomat H, Nabavi N, Behmanesh H, Zhai B, Dagil R, Choudhary S, Gustavsson T, Clausen TM, Esko JD, Allen JW, Thompson MA, Tran NL, Moldvay J, Dome B, Salanti A, Al-Nakouzi N, Weiss GJ, Daugaard M. Oo HZ, et al. Among authors: adomat h. Cancers (Basel). 2021 Sep 6;13(17):4489. doi: 10.3390/cancers13174489. Cancers (Basel). 2021. PMID: 34503301 Free PMC article.
Reformation of the chondroitin sulfate glycocalyx enables progression of AR-independent prostate cancer.
Al-Nakouzi N, Wang CK, Oo HZ, Nelepcu I, Lallous N, Spliid CB, Khazamipour N, Lo J, Truong S, Collins C, Hui D, Esfandnia S, Adomat H, Clausen TM, Gustavsson T, Choudhary S, Dagil R, Corey E, Wang Y, Chauchereau A, Fazli L, Esko JD, Salanti A, Nelson PS, Gleave ME, Daugaard M. Al-Nakouzi N, et al. Among authors: adomat h. Nat Commun. 2022 Aug 13;13(1):4760. doi: 10.1038/s41467-022-32530-7. Nat Commun. 2022. PMID: 35963852 Free PMC article.
A Bifunctional PARP-HDAC Inhibitor with Activity in Ewing Sarcoma.
Ramos L, Truong S, Zhai B, Joshi J, Ghaidi F, Lizardo MM, Shyp T, Kung SHY, Rezakhanlou AM, Oo HZ, Adomat H, Le Bihan S, Collins C, Bacha J, Brown D, Langlands J, Shen W, Lallous N, Sorensen PH, Daugaard M. Ramos L, et al. Among authors: adomat h. Clin Cancer Res. 2023 Sep 1;29(17):3541-3553. doi: 10.1158/1078-0432.CCR-22-3897. Clin Cancer Res. 2023. PMID: 37279093 Free PMC article.
The Placental Gene PEG10 Promotes Progression of Neuroendocrine Prostate Cancer.
Akamatsu S, Wyatt AW, Lin D, Lysakowski S, Zhang F, Kim S, Tse C, Wang K, Mo F, Haegert A, Brahmbhatt S, Bell R, Adomat H, Kawai Y, Xue H, Dong X, Fazli L, Tsai H, Lotan TL, Kossai M, Mosquera JM, Rubin MA, Beltran H, Zoubeidi A, Wang Y, Gleave ME, Collins CC. Akamatsu S, et al. Among authors: adomat h. Cell Rep. 2015 Aug 11;12(6):922-36. doi: 10.1016/j.celrep.2015.07.012. Epub 2015 Jul 30. Cell Rep. 2015. PMID: 26235627 Free article.
91 results