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Removal of senescent cells reduces the viral load and attenuates pulmonary and systemic inflammation in SARS-CoV-2-infected, aged hamsters.
Delval L, Hantute-Ghesquier A, Sencio V, Flaman JM, Robil C, Angulo FS, Lipskaia L, Çobanoğlu O, Lacoste AS, Machelart A, Danneels A, Corbin M, Deruyter L, Heumel S, Idziorek T, Séron K, Sauve F, Bongiovanni A, Prévot V, Wolowczuk I, Belouzard S, Saliou JM, Gosset P, Bernard D, Rouillé Y, Adnot S, Duterque-Coquillaud M, Trottein F. Delval L, et al. Among authors: adnot s. Nat Aging. 2023 Jul;3(7):829-845. doi: 10.1038/s43587-023-00442-w. Epub 2023 Jul 6. Nat Aging. 2023. PMID: 37414987 Free PMC article.
Osteopontin promotes age-related adipose tissue remodeling through senescence-associated macrophage dysfunction.
Sawaki D, Zhang Y, Mohamadi A, Pini M, Mezdari Z, Lipskaia L, Naushad S, Lamendour L, Altintas DM, Breau M, Liang H, Halfaoui M, Delmont T, Surenaud M, Rousseau D, Yoshimitsu T, Louache F, Adnot S, Henegar C, Gual P, Czibik G, Derumeaux G. Sawaki D, et al. Among authors: adnot s. JCI Insight. 2023 Apr 24;8(8):e145811. doi: 10.1172/jci.insight.145811. JCI Insight. 2023. PMID: 37092554 Free PMC article.
mTert induction in p21-positive cells counteracts capillary rarefaction and pulmonary emphysema.
Lipskaia L, Breau M, Cayrou C, Churikov D, Braud L, Jacquet J, Born E, Fouillade C, Curras-Alonso S, Bauwens S, Jourquin F, Fiore F, Castellano R, Josselin E, Sánchez-Ferrer C, Giovinazzo G, Lachaud C, Gilson E, Flores I, Londono-Vallejo A, Adnot S, Géli V. Lipskaia L, et al. Among authors: adnot s. EMBO Rep. 2024 Mar;25(3):1650-1684. doi: 10.1038/s44319-023-00041-1. Epub 2024 Feb 29. EMBO Rep. 2024. PMID: 38424230 Free PMC article.
Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression.
Born E, Lipskaia L, Breau M, Houssaini A, Beaulieu D, Marcos E, Pierre R, Do Cruzeiro M, Lefevre M, Derumeaux G, Bulavin DV, Delcroix M, Quarck R, Reen V, Gil J, Bernard D, Flaman JM, Adnot S, Abid S. Born E, et al. Among authors: adnot s. Circulation. 2023 Feb 21;147(8):650-666. doi: 10.1161/CIRCULATIONAHA.122.058794. Epub 2022 Dec 14. Circulation. 2023. PMID: 36515093
259 results