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Culture media composition influences patient-derived organoid ability to predict therapeutic responses in gastrointestinal cancers.
Hogenson TL, Xie H, Phillips WJ, Toruner MD, Li JJ, Horn IP, Kennedy DJ, Almada LL, Marks DL, Carr RM, Toruner M, Sigafoos AN, Koenig-Kappes AN, Olson RL, Tolosa EJ, Zhang C, Li H, Doles JD, Bleeker J, Barrett MT, Boyum JH, Kipp BR, Mahipal A, Hubbard JM, Scheffler Hanson TJ, Petersen GM, Dasari S, Oberg AL, Truty MJ, Graham RP, Levy MJ, Zhu M, Billadeau DD, Adjei AA, Dusetti N, Iovanna JL, Bekaii-Saab TS, Ma WW, Fernandez-Zapico ME. Hogenson TL, et al. Among authors: adjei aa. JCI Insight. 2022 Nov 22;7(22):e158060. doi: 10.1172/jci.insight.158060. JCI Insight. 2022. PMID: 36256477 Free PMC article.
Novel agents on the horizon for cancer therapy.
Ma WW, Adjei AA. Ma WW, et al. Among authors: adjei aa. CA Cancer J Clin. 2009 Mar-Apr;59(2):111-37. doi: 10.3322/caac.20003. CA Cancer J Clin. 2009. PMID: 19278961 Free article. Review.
Targeting of the Hedgehog/GLI and mTOR pathways in advanced pancreatic cancer, a phase 1 trial of Vismodegib and Sirolimus combination.
Carr RM, Duma N, McCleary-Wheeler AL, Almada LL, Marks DL, Graham RP, Smyrk TC, Lowe V, Borad MJ, Kim G, Johnson GB, Allred JB, Yin J, Lim VS, Bekaii-Saab T, Ma WW, Erlichman C, Adjei AA, Fernandez-Zapico ME. Carr RM, et al. Among authors: adjei aa. Pancreatology. 2020 Sep;20(6):1115-1122. doi: 10.1016/j.pan.2020.06.015. Epub 2020 Jul 14. Pancreatology. 2020. PMID: 32778368
Biomarker Discovery and Validation: Statistical Considerations.
Ou FS, Michiels S, Shyr Y, Adjei AA, Oberg AL. Ou FS, et al. Among authors: adjei aa. J Thorac Oncol. 2021 Apr;16(4):537-545. doi: 10.1016/j.jtho.2021.01.1616. Epub 2021 Feb 2. J Thorac Oncol. 2021. PMID: 33545385 Free PMC article.
A phase I pharmacokinetic and safety study of Paclitaxel Injection Concentrate for Nano-dispersion (PICN) alone and in combination with carboplatin in patients with advanced solid malignancies and biliary tract cancers.
Ma WW, Zhu M, Lam ET, Diamond JR, Dy GK, Fisher GA, Goff LW, Alberts S, Bui LA, Sanghal A, Kothekar M, Khopade A, Chimote G, Faulkner R, Eckhardt SG, Adjei AA, Jimeno A. Ma WW, et al. Among authors: adjei aa. Cancer Chemother Pharmacol. 2021 Jun;87(6):779-788. doi: 10.1007/s00280-021-04235-z. Epub 2021 Feb 26. Cancer Chemother Pharmacol. 2021. PMID: 33634324 Clinical Trial.
457 results