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Lactate induces metabolic and epigenetic reprogramming of pro-inflammatory Th17 cells.
Lopez Krol A, Nehring HP, Krause FF, Wempe A, Raifer H, Nist A, Stiewe T, Bertrams W, Schmeck B, Luu M, Leister H, Chung HR, Bauer UM, Adhikary T, Visekruna A. Lopez Krol A, et al. Among authors: adhikary t. EMBO Rep. 2022 Dec 6;23(12):e54685. doi: 10.15252/embr.202254685. Epub 2022 Oct 10. EMBO Rep. 2022. PMID: 36215678 Free PMC article.
Deregulation of PPARβ/δ target genes in tumor-associated macrophages by fatty acid ligands in the ovarian cancer microenvironment.
Schumann T, Adhikary T, Wortmann A, Finkernagel F, Lieber S, Schnitzer E, Legrand N, Schober Y, Nockher WA, Toth PM, Diederich WE, Nist A, Stiewe T, Wagner U, Reinartz S, Müller-Brüsselbach S, Müller R. Schumann T, et al. Among authors: adhikary t. Oncotarget. 2015 May 30;6(15):13416-33. doi: 10.18632/oncotarget.3826. Oncotarget. 2015. PMID: 25968567 Free PMC article.
The transcriptional signature of human ovarian carcinoma macrophages is associated with extracellular matrix reorganization.
Finkernagel F, Reinartz S, Lieber S, Adhikary T, Wortmann A, Hoffmann N, Bieringer T, Nist A, Stiewe T, Jansen JM, Wagner U, Müller-Brüsselbach S, Müller R. Finkernagel F, et al. Among authors: adhikary t. Oncotarget. 2016 Nov 15;7(46):75339-75352. doi: 10.18632/oncotarget.12180. Oncotarget. 2016. PMID: 27659538 Free PMC article.
Proteotranscriptomics Reveal Signaling Networks in the Ovarian Cancer Microenvironment.
Worzfeld T, Finkernagel F, Reinartz S, Konzer A, Adhikary T, Nist A, Stiewe T, Wagner U, Looso M, Graumann J, Müller R. Worzfeld T, et al. Among authors: adhikary t. Mol Cell Proteomics. 2018 Feb;17(2):270-289. doi: 10.1074/mcp.RA117.000400. Epub 2017 Nov 15. Mol Cell Proteomics. 2018. PMID: 29141914 Free PMC article.
Chromatin Binding of c-REL and p65 Is Not Limiting for Macrophage IL12B Transcription During Immediate Suppression by Ovarian Carcinoma Ascites.
Unger A, Finkernagel F, Hoffmann N, Neuhaus F, Joos B, Nist A, Stiewe T, Visekruna A, Wagner U, Reinartz S, Müller-Brüsselbach S, Müller R, Adhikary T. Unger A, et al. Among authors: adhikary t. Front Immunol. 2018 Jun 27;9:1425. doi: 10.3389/fimmu.2018.01425. eCollection 2018. Front Immunol. 2018. PMID: 29997615 Free PMC article.
The short-chain fatty acid pentanoate suppresses autoimmunity by modulating the metabolic-epigenetic crosstalk in lymphocytes.
Luu M, Pautz S, Kohl V, Singh R, Romero R, Lucas S, Hofmann J, Raifer H, Vachharajani N, Carrascosa LC, Lamp B, Nist A, Stiewe T, Shaul Y, Adhikary T, Zaiss MM, Lauth M, Steinhoff U, Visekruna A. Luu M, et al. Among authors: adhikary t. Nat Commun. 2019 Feb 15;10(1):760. doi: 10.1038/s41467-019-08711-2. Nat Commun. 2019. PMID: 30770822 Free PMC article.
42 results