Adams J - Search Results

1

Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S. Steinhart Z, et al. Among authors: adams j. Nat Med. 2017 Jan;23(1):60-68. doi: 10.1038/nm.4219. Epub 2016 Nov 21. Nat Med. 2017. PMID: 27869803

2

CDR-H3 diversity is not required for antigen recognition by synthetic antibodies.

Persson H, Ye W, Wernimont A, Adams JJ, Koide A, Koide S, Lam R, Sidhu SS. Persson H, et al. Among authors: adams jj. J Mol Biol. 2013 Feb 22;425(4):803-11. doi: 10.1016/j.jmb.2012.11.037. Epub 2012 Dec 3. J Mol Biol. 2013. PMID: 23219464 Free PMC article.

3

Recombinant genetic libraries and human monoclonal antibodies.

Adams JJ, Nelson B, Sidhu SS. Adams JJ, et al. Methods Mol Biol. 2014;1060:149-70. doi: 10.1007/978-1-62703-586-6_9. Methods Mol Biol. 2014. PMID: 24037841

4

Synthetic antibody technologies.

Adams JJ, Sidhu SS. Adams JJ, et al. Curr Opin Struct Biol. 2014 Feb;24:1-9. doi: 10.1016/j.sbi.2013.11.003. Epub 2013 Dec 4. Curr Opin Struct Biol. 2014. PMID: 24721448 Review.

5

Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity.

Adams JJ, Narayanan S, Birnbaum ME, Sidhu SS, Blevins SJ, Gee MH, Sibener LV, Baker BM, Kranz DM, Garcia KC. Adams JJ, et al. Nat Immunol. 2016 Jan;17(1):87-94. doi: 10.1038/ni.3310. Epub 2015 Nov 2. Nat Immunol. 2016. PMID: 26523866 Free PMC article.

6

A Potent d-Protein Antagonist of VEGF-A is Nonimmunogenic, Metabolically Stable, and Longer-Circulating in Vivo.

Uppalapati M, Lee DJ, Mandal K, Li H, Miranda LP, Lowitz J, Kenney J, Adams JJ, Ault-Riché D, Kent SB, Sidhu SS. Uppalapati M, et al. Among authors: adams jj. ACS Chem Biol. 2016 Apr 15;11(4):1058-65. doi: 10.1021/acschembio.5b01006. Epub 2016 Feb 3. ACS Chem Biol. 2016. PMID: 26745345

7

A novel immunotherapy targeting MMP-14 limits hypoxia, immune suppression and metastasis in triple-negative breast cancer models.

Ling B, Watt K, Banerjee S, Newsted D, Truesdell P, Adams J, Sidhu SS, Craig AWB. Ling B, et al. Among authors: adams j. Oncotarget. 2017 May 9;8(35):58372-58385. doi: 10.18632/oncotarget.17702. eCollection 2017 Aug 29. Oncotarget. 2017. PMID: 28938563 Free PMC article.

8

Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors.

Steinhart Z, Pavlovic Z, Chandrashekhar M, Hart T, Wang X, Zhang X, Robitaille M, Brown KR, Jaksani S, Overmeer R, Boj SF, Adams J, Pan J, Clevers H, Sidhu S, Moffat J, Angers S. Steinhart Z, et al. Among authors: adams j. Nat Med. 2017 Nov 7;23(11):1384. doi: 10.1038/nm1117-1384d. Nat Med. 2017. PMID: 29117169

9

Highly multiplexed and quantitative cell-surface protein profiling using genetically barcoded antibodies.

Pollock SB, Hu A, Mou Y, Martinko AJ, Julien O, Hornsby M, Ploder L, Adams JJ, Geng H, Müschen M, Sidhu SS, Moffat J, Wells JA. Pollock SB, et al. Among authors: adams jj. Proc Natl Acad Sci U S A. 2018 Mar 13;115(11):2836-2841. doi: 10.1073/pnas.1721899115. Epub 2018 Feb 23. Proc Natl Acad Sci U S A. 2018. PMID: 29476010 Free PMC article.

10

Cotargeting Ephrin Receptor Tyrosine Kinases A2 and A3 in Cancer Stem Cells Reduces Growth of Recurrent Glioblastoma.

Qazi MA, Vora P, Venugopal C, Adams J, Singh M, Hu A, Gorelik M, Subapanditha MK, Savage N, Yang J, Chokshi C, London M, Gont A, Bobrowski D, Grinshtein N, Brown KR, Murty NK, Nilvebrant J, Kaplan D, Moffat J, Sidhu S, Singh SK. Qazi MA, et al. Among authors: adams j. Cancer Res. 2018 Sep 1;78(17):5023-5037. doi: 10.1158/0008-5472.CAN-18-0267. Epub 2018 Jun 26. Cancer Res. 2018. PMID: 29945963

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