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Page 1
Mechanisms through which lithocholic acid delays yeast chronological aging under caloric restriction conditions.
Arlia-Ciommo A, Leonov A, Mohammad K, Beach A, Richard VR, Bourque SD, Burstein MT, Goldberg AA, Kyryakov P, Gomez-Perez A, Koupaki O, Titorenko VI. Arlia-Ciommo A, et al. Among authors: beach a. Oncotarget. 2018 Oct 9;9(79):34945-34971. doi: 10.18632/oncotarget.26188. eCollection 2018 Oct 9. Oncotarget. 2018. PMID: 30405886 Free PMC article.
Caloric restriction delays yeast chronological aging by remodeling carbohydrate and lipid metabolism, altering peroxisomal and mitochondrial functionalities, and postponing the onsets of apoptotic and liponecrotic modes of regulated cell death.
Arlia-Ciommo A, Leonov A, Beach A, Richard VR, Bourque SD, Burstein MT, Kyryakov P, Gomez-Perez A, Koupaki O, Feldman R, Titorenko VI. Arlia-Ciommo A, et al. Among authors: beach a. Oncotarget. 2018 Mar 5;9(22):16163-16184. doi: 10.18632/oncotarget.24604. eCollection 2018 Mar 23. Oncotarget. 2018. PMID: 29662634 Free PMC article.
Mechanism of liponecrosis, a distinct mode of programmed cell death.
Richard VR, Beach A, Piano A, Leonov A, Feldman R, Burstein MT, Kyryakov P, Gomez-Perez A, Arlia-Ciommo A, Baptista S, Campbell C, Goncharov D, Pannu S, Patrinos D, Sadri B, Svistkova V, Victor A, Titorenko VI. Richard VR, et al. Among authors: beach a. Cell Cycle. 2014;13(23):3707-26. doi: 10.4161/15384101.2014.965003. Cell Cycle. 2014. PMID: 25483081 Free PMC article.
Mitochondrial membrane lipidome defines yeast longevity.
Beach A, Richard VR, Leonov A, Burstein MT, Bourque SD, Koupaki O, Juneau M, Feldman R, Iouk T, Titorenko VI. Beach A, et al. Aging (Albany NY). 2013 Jul;5(7):551-74. doi: 10.18632/aging.100578. Aging (Albany NY). 2013. PMID: 23924582 Free PMC article.
Macromitophagy is a longevity assurance process that in chronologically aging yeast limited in calorie supply sustains functional mitochondria and maintains cellular lipid homeostasis.
Richard VR, Leonov A, Beach A, Burstein MT, Koupaki O, Gomez-Perez A, Levy S, Pluska L, Mattie S, Rafesh R, Iouk T, Sheibani S, Greenwood M, Vali H, Titorenko VI. Richard VR, et al. Among authors: beach a. Aging (Albany NY). 2013 Apr;5(4):234-69. doi: 10.18632/aging.100547. Aging (Albany NY). 2013. PMID: 23553280 Free PMC article.
19 results