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Old Things New View: Ascorbic Acid Protects the Brain in Neurodegenerative Disorders.
Int J Mol Sci. 2015 Nov 27;16(12):28194-217. doi: 10.3390/ijms161226095.
Int J Mol Sci. 2015.
PMID: 26633354
Free PMC article.
Review.
Beyond the redox imbalance: Oxidative stress contributes to an impaired GLUT3 modulation in Huntington's disease.
Covarrubias-Pinto A, Moll P, Solís-Maldonado M, Acuña AI, Riveros A, Miró MP, Papic E, Beltrán FA, Cepeda C, Concha II, Brauchi S, Castro MA.
Covarrubias-Pinto A, et al. Among authors: acuna ai.
Free Radic Biol Med. 2015 Dec;89:1085-96. doi: 10.1016/j.freeradbiomed.2015.09.024. Epub 2015 Oct 9.
Free Radic Biol Med. 2015.
PMID: 26456058
Free PMC article.
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Ascorbic acid increases SVCT2 localization at the plasma membrane by accelerating its trafficking from early secretory compartments and through the endocytic-recycling pathway.
Covarrubias-Pinto A, Acuña AI, Boncompain G, Papic E, Burgos PV, Perez F, Castro MA.
Covarrubias-Pinto A, et al. Among authors: acuna ai.
Free Radic Biol Med. 2018 May 20;120:181-191. doi: 10.1016/j.freeradbiomed.2018.03.013. Epub 2018 Mar 12.
Free Radic Biol Med. 2018.
PMID: 29545069
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Ascorbic acid-dependent GLUT3 inhibition is a critical step for switching neuronal metabolism.
Beltrán FA, Acuña AI, Miró MP, Angulo C, Concha II, Castro MA.
Beltrán FA, et al. Among authors: acuna ai.
J Cell Physiol. 2011 Dec;226(12):3286-94. doi: 10.1002/jcp.22674.
J Cell Physiol. 2011.
PMID: 21321936
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A failure in energy metabolism and antioxidant uptake precede symptoms of Huntington's disease in mice.
Acuña AI, Esparza M, Kramm C, Beltrán FA, Parra AV, Cepeda C, Toro CA, Vidal RL, Hetz C, Concha II, Brauchi S, Levine MS, Castro MA.
Acuña AI, et al.
Nat Commun. 2013;4:2917. doi: 10.1038/ncomms3917.
Nat Commun. 2013.
PMID: 24336051
Free PMC article.
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Altered lactate metabolism in Huntington's disease is dependent on GLUT3 expression.
Solís-Maldonado M, Miró MP, Acuña AI, Covarrubias-Pinto A, Loaiza A, Mayorga G, Beltrán FA, Cepeda C, Levine MS, Concha II, Bátiz LF, Carrasco MA, Castro MA.
Solís-Maldonado M, et al. Among authors: acuna ai.
CNS Neurosci Ther. 2018 Apr;24(4):343-352. doi: 10.1111/cns.12837.
CNS Neurosci Ther. 2018.
PMID: 29582588
Free PMC article.
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Muscle glycogen synthase isoform is responsible for testicular glycogen synthesis: glycogen overproduction induces apoptosis in male germ cells.
Villarroel-Espíndola F, Maldonado R, Mancilla H, vander Stelt K, Acuña AI, Covarrubias A, López C, Angulo C, Castro MA, Slebe JC, Durán J, García-Rocha M, Guinovart JJ, Concha II.
Villarroel-Espíndola F, et al. Among authors: acuna ai.
J Cell Biochem. 2013 Jul;114(7):1653-64. doi: 10.1002/jcb.24507.
J Cell Biochem. 2013.
PMID: 23386391
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