Actis Dato V - Search Results

1

LRP1-Mediated AggLDL Endocytosis Promotes Cholesteryl Ester Accumulation and Impairs Insulin Response in HL-1 Cells.

Actis Dato V, Benitez-Amaro A, de Gonzalo-Calvo D, Vazquez M, Bonacci G, Llorente-Cortés V, Chiabrando GA. Actis Dato V, et al. Cells. 2020 Jan 10;9(1):182. doi: 10.3390/cells9010182. Cells. 2020. PMID: 31936892 Free PMC article.

2

Insulin-induced exocytosis regulates the cell surface level of low-density lipoprotein-related protein-1 in Müller Glial cells.

Actis Dato V, Grosso RA, Sánchez MC, Fader CM, Chiabrando GA. Actis Dato V, et al. Biochem J. 2018 May 15;475(9):1669-1685. doi: 10.1042/BCJ20170891. Biochem J. 2018. PMID: 29669912

3

The Role of Low-Density Lipoprotein Receptor-Related Protein 1 in Lipid Metabolism, Glucose Homeostasis and Inflammation.

Actis Dato V, Chiabrando GA. Actis Dato V, et al. Int J Mol Sci. 2018 Jun 15;19(6):1780. doi: 10.3390/ijms19061780. Int J Mol Sci. 2018. PMID: 29914093 Free PMC article. Review.

4

Activated α₂-Macroglobulin Regulates LRP1 Levels at the Plasma Membrane through the Activation of a Rab10-dependent Exocytic Pathway in Retinal Müller Glial Cells.

Jaldín-Fincati JR, Actis Dato V, Díaz NM, Sánchez MC, Barcelona PF, Chiabrando GA. Jaldín-Fincati JR, et al. Among authors: actis dato v. Sci Rep. 2019 Sep 13;9(1):13234. doi: 10.1038/s41598-019-49072-6. Sci Rep. 2019. PMID: 31519919 Free PMC article.

5

LRP1 mediates the IGF-1-induced GLUT1 expression on the cell surface and glucose uptake in Müller glial cells.

Actis Dato V, Sánchez MC, Chiabrando GA. Actis Dato V, et al. Sci Rep. 2021 Feb 26;11(1):4742. doi: 10.1038/s41598-021-84090-3. Sci Rep. 2021. PMID: 33637845 Free PMC article.

6

Activated Alpha-2 Macroglobulin Improves Insulin Response via LRP1 in Lipid-Loaded HL-1 Cardiomyocytes.

Actis Dato V, Chiabrando GA. Actis Dato V, et al. Int J Mol Sci. 2021 Jun 28;22(13):6915. doi: 10.3390/ijms22136915. Int J Mol Sci. 2021. PMID: 34203120 Free PMC article.

7

Targeting cholesteryl ester accumulation in the heart improves cardiac insulin response.

Actis Dato V, Benitez-Amaro A, Garcia E, Claudi L, Lhoëst MTL, Iborra A, Escola-Gil JC, Guerra JM, Samouillan V, Enrich C, Chiabrando G, Llorente-Cortés V. Actis Dato V, et al. Biomed Pharmacother. 2022 Aug;152:113270. doi: 10.1016/j.biopha.2022.113270. Epub 2022 Jun 13. Biomed Pharmacother. 2022. PMID: 35709652 Free article.

8

Decreased low-density lipoprotein receptor-related protein 1 expression in pro-inflammatory monocytes is associated with subclinical atherosclerosis.

Albertini RA, Nicolas JC, Actis Dato V, Ferrer DG, Tinti ME, Capra RH, Chiabrando GA. Albertini RA, et al. Among authors: actis dato v. Front Cardiovasc Med. 2022 Jul 26;9:949778. doi: 10.3389/fcvm.2022.949778. eCollection 2022. Front Cardiovasc Med. 2022. PMID: 35958411 Free PMC article.

9

Inhibitory Effects of LRP1-Based Immunotherapy on Cardiac Extracellular Matrix Biophysical Alterations Induced by Hypercholesterolemia.

Samouillan V, Garcia E, Benitez-Amaro A, La Chica Lhoëst MT, Dandurand J, Actis Dato V, Guerra JM, Escolà-Gil JC, Chiabrando G, Enrich C, Llorente-Cortes V. Samouillan V, et al. Among authors: actis dato v. J Med Chem. 2023 May 11;66(9):6251-6262. doi: 10.1021/acs.jmedchem.2c02103. Epub 2023 Apr 28. J Med Chem. 2023. PMID: 37116069 Free PMC article.

10

Transcriptional analysis reveals that the intracellular lipid accumulation impairs gene expression profiles involved in insulin response-associated cardiac functionality.

Actis Dato V, Paz MC, Rey FE, Sánchez MC, Llorente-Cortés V, Chiabrando GA, Ceschin DG. Actis Dato V, et al. Sci Rep. 2023 May 30;13(1):8761. doi: 10.1038/s41598-023-35951-6. Sci Rep. 2023. PMID: 37253991 Free PMC article.

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