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A complex secretory program orchestrated by the inflammasome controls paracrine senescence.
Acosta JC, Banito A, Wuestefeld T, Georgilis A, Janich P, Morton JP, Athineos D, Kang TW, Lasitschka F, Andrulis M, Pascual G, Morris KJ, Khan S, Jin H, Dharmalingam G, Snijders AP, Carroll T, Capper D, Pritchard C, Inman GJ, Longerich T, Sansom OJ, Benitah SA, Zender L, Gil J. Acosta JC, et al. Nat Cell Biol. 2013 Aug;15(8):978-90. doi: 10.1038/ncb2784. Epub 2013 Jun 16. Nat Cell Biol. 2013. PMID: 23770676 Free PMC article.
Chemokine signaling via the CXCR2 receptor reinforces senescence.
Acosta JC, O'Loghlen A, Banito A, Guijarro MV, Augert A, Raguz S, Fumagalli M, Da Costa M, Brown C, Popov N, Takatsu Y, Melamed J, d'Adda di Fagagna F, Bernard D, Hernando E, Gil J. Acosta JC, et al. Cell. 2008 Jun 13;133(6):1006-18. doi: 10.1016/j.cell.2008.03.038. Cell. 2008. PMID: 18555777 Free article.
Control of senescence by CXCR2 and its ligands.
Acosta JC, O'Loghlen A, Banito A, Raguz S, Gil J. Acosta JC, et al. Cell Cycle. 2008 Oct;7(19):2956-9. doi: 10.4161/cc.7.19.6780. Epub 2008 Oct 13. Cell Cycle. 2008. PMID: 18838863 Review.
Senescence impairs successful reprogramming to pluripotent stem cells.
Banito A, Rashid ST, Acosta JC, Li S, Pereira CF, Geti I, Pinho S, Silva JC, Azuara V, Walsh M, Vallier L, Gil J. Banito A, et al. Among authors: acosta jc. Genes Dev. 2009 Sep 15;23(18):2134-9. doi: 10.1101/gad.1811609. Epub 2009 Aug 20. Genes Dev. 2009. PMID: 19696146 Free PMC article.
Senescence: a new weapon for cancer therapy.
Acosta JC, Gil J. Acosta JC, et al. Trends Cell Biol. 2012 Apr;22(4):211-9. doi: 10.1016/j.tcb.2011.11.006. Epub 2012 Jan 13. Trends Cell Biol. 2012. PMID: 22245068 Review.
mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype.
Herranz N, Gallage S, Mellone M, Wuestefeld T, Klotz S, Hanley CJ, Raguz S, Acosta JC, Innes AJ, Banito A, Georgilis A, Montoya A, Wolter K, Dharmalingam G, Faull P, Carroll T, Martínez-Barbera JP, Cutillas P, Reisinger F, Heikenwalder M, Miller RA, Withers D, Zender L, Thomas GJ, Gil J. Herranz N, et al. Among authors: acosta jc. Nat Cell Biol. 2015 Sep;17(9):1205-17. doi: 10.1038/ncb3225. Epub 2015 Aug 17. Nat Cell Biol. 2015. PMID: 26280535 Free PMC article.
84 results