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Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas.
Panwalkar P, Tamrazi B, Dang D, Chung C, Sweha S, Natarajan SK, Pun M, Bayliss J, Ogrodzinski MP, Pratt D, Mullan B, Hawes D, Yang F, Lu C, Sabari BR, Achreja A, Heon J, Animasahun O, Cieslik M, Dunham C, Yip S, Hukin J, Phillips JJ, Bornhorst M, Griesinger AM, Donson AM, Foreman NK, Garton HJL, Heth J, Muraszko K, Nazarian J, Koschmann C, Jiang L, Filbin MG, Nagrath D, Kool M, Korshunov A, Pfister SM, Gilbertson RJ, Allis CD, Chinnaiyan AM, Lunt SY, Blüml S, Judkins AR, Venneti S. Panwalkar P, et al. Among authors: achreja a. Sci Transl Med. 2021 Oct 6;13(614):eabc0497. doi: 10.1126/scitranslmed.abc0497. Epub 2021 Oct 6. Sci Transl Med. 2021. PMID: 34613815 Free PMC article.
Nitric Oxide: The Forgotten Child of Tumor Metabolism.
Salimian Rizi B, Achreja A, Nagrath D. Salimian Rizi B, et al. Among authors: achreja a. Trends Cancer. 2017 Sep;3(9):659-672. doi: 10.1016/j.trecan.2017.07.005. Epub 2017 Aug 18. Trends Cancer. 2017. PMID: 28867169 Free PMC article. Review.
Cellular Location of HNF4α is Linked With Terminal Liver Failure in Humans.
Florentino RM, Fraunhoffer NA, Morita K, Takeishi K, Ostrowska A, Achreja A, Animasahun O, Haep N, Arazov S, Agarwal N, Collin de l'Hortet A, Guzman-Lepe J, Tafaleng EN, Mukherjee A, Troy K, Banerjee S, Paranjpe S, Michalopoulos GK, Bell A, Nagrath D, Hainer SJ, Fox IJ, Soto-Gutierrez A. Florentino RM, et al. Among authors: achreja a. Hepatol Commun. 2020 Apr 21;4(6):859-875. doi: 10.1002/hep4.1505. eCollection 2020 Jun. Hepatol Commun. 2020. PMID: 32490322 Free PMC article.
Tumour-reprogrammed stromal BCAT1 fuels branched-chain ketoacid dependency in stromal-rich PDAC tumours.
Zhu Z, Achreja A, Meurs N, Animasahun O, Owen S, Mittal A, Parikh P, Lo TW, Franco-Barraza J, Shi J, Gunchick V, Sherman MH, Cukierman E, Pickering AM, Maitra A, Sahai V, Morgan MA, Nagrath S, Lawrence TS, Nagrath D. Zhu Z, et al. Among authors: achreja a. Nat Metab. 2020 Aug;2(8):775-792. doi: 10.1038/s42255-020-0226-5. Epub 2020 Jul 6. Nat Metab. 2020. PMID: 32694827 Free PMC article.
Metabolic collateral lethal target identification reveals MTHFD2 paralogue dependency in ovarian cancer.
Achreja A, Yu T, Mittal A, Choppara S, Animasahun O, Nenwani M, Wuchu F, Meurs N, Mohan A, Jeon JH, Sarangi I, Jayaraman A, Owen S, Kulkarni R, Cusato M, Weinberg F, Kweon HK, Subramanian C, Wicha MS, Merajver SD, Nagrath S, Cho KR, DiFeo A, Lu X, Nagrath D. Achreja A, et al. Nat Metab. 2022 Sep;4(9):1119-1137. doi: 10.1038/s42255-022-00636-3. Epub 2022 Sep 21. Nat Metab. 2022. PMID: 36131208
Therapeutic implications of mitochondrial stress-induced proteasome inhibitor resistance in multiple myeloma.
Sharma A, Nair R, Achreja A, Mittal A, Gupta P, Balakrishnan K, Edgar CL, Animasahun O, Dwivedi B, Barwick BG, Gupta VA, Matulis SM, Bhasin M, Lonial S, Nooka AK, Wiita AP, Boise LH, Nagrath D, Shanmugam M. Sharma A, et al. Among authors: achreja a. Sci Adv. 2022 Sep 30;8(39):eabq5575. doi: 10.1126/sciadv.abq5575. Epub 2022 Sep 28. Sci Adv. 2022. PMID: 36170375 Free PMC article.
29 results