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Page 1
Comparison of in Silico, Electrochemical, in Vitro and in Vivo Metabolism of a Homologous Series of (Radio)fluorinated σ1 Receptor Ligands Designed for Positron Emission Tomography.
Wiese C, Große Maestrup E, Galla F, Schepmann D, Hiller A, Fischer S, Ludwig FA, Deuther-Conrad W, Donat CK, Brust P, Büter L, Karst U, Wünsch B. Wiese C, et al. Among authors: hiller a. ChemMedChem. 2016 Nov 7;11(21):2445-2458. doi: 10.1002/cmdc.201600366. Epub 2016 Sep 28. ChemMedChem. 2016. PMID: 27677767
Distinctive in vivo kinetics of the new σ1 receptor ligands (R)-(+)- and (S)-(-)-18F-fluspidine in porcine brain.
Brust P, Deuther-Conrad W, Becker G, Patt M, Donat CK, Stittsworth S, Fischer S, Hiller A, Wenzel B, Dukic-Stefanovic S, Hesse S, Steinbach J, Wünsch B, Lever SZ, Sabri O. Brust P, et al. Among authors: hiller a. J Nucl Med. 2014 Oct;55(10):1730-6. doi: 10.2967/jnumed.114.137562. Epub 2014 Jul 28. J Nucl Med. 2014. PMID: 25071097 Free article.
Synthesis and biological evaluation of both enantiomers of [(18)F]flubatine, promising radiotracers with fast kinetics for the imaging of α4β2-nicotinic acetylcholine receptors.
Smits R, Fischer S, Hiller A, Deuther-Conrad W, Wenzel B, Patt M, Cumming P, Steinbach J, Sabri O, Brust P, Hoepping A. Smits R, et al. Among authors: hiller a. Bioorg Med Chem. 2014 Jan 15;22(2):804-12. doi: 10.1016/j.bmc.2013.12.011. Epub 2013 Dec 12. Bioorg Med Chem. 2014. PMID: 24369841
Use of 3-[(18)F]fluoropropanesulfonyl chloride as a prosthetic agent for the radiolabelling of amines: Investigation of precursor molecules, labelling conditions and enzymatic stability of the corresponding sulfonamides.
Löser R, Fischer S, Hiller A, Köckerling M, Funke U, Maisonial A, Brust P, Steinbach J. Löser R, et al. Among authors: hiller a. Beilstein J Org Chem. 2013 May 27;9:1002-11. doi: 10.3762/bjoc.9.115. Print 2013. Beilstein J Org Chem. 2013. PMID: 23766817 Free PMC article.
24 results