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Page 1
Controlling the SARS-CoV-2 spike glycoprotein conformation.
Henderson R, Edwards RJ, Mansouri K, Janowska K, Stalls V, Gobeil SMC, Kopp M, Li D, Parks R, Hsu AL, Borgnia MJ, Haynes BF, Acharya P. Henderson R, et al. Among authors: acharya p. Nat Struct Mol Biol. 2020 Oct;27(10):925-933. doi: 10.1038/s41594-020-0479-4. Epub 2020 Jul 22. Nat Struct Mol Biol. 2020. PMID: 32699321 Free PMC article.
Structure and immune recognition of trimeric pre-fusion HIV-1 Env.
Pancera M, Zhou T, Druz A, Georgiev IS, Soto C, Gorman J, Huang J, Acharya P, Chuang GY, Ofek G, Stewart-Jones GB, Stuckey J, Bailer RT, Joyce MG, Louder MK, Tumba N, Yang Y, Zhang B, Cohen MS, Haynes BF, Mascola JR, Morris L, Munro JB, Blanchard SC, Mothes W, Connors M, Kwong PD. Pancera M, et al. Among authors: acharya p. Nature. 2014 Oct 23;514(7523):455-61. doi: 10.1038/nature13808. Epub 2014 Oct 8. Nature. 2014. PMID: 25296255 Free PMC article.
Structural Repertoire of HIV-1-Neutralizing Antibodies Targeting the CD4 Supersite in 14 Donors.
Zhou T, Lynch RM, Chen L, Acharya P, Wu X, Doria-Rose NA, Joyce MG, Lingwood D, Soto C, Bailer RT, Ernandes MJ, Kong R, Longo NS, Louder MK, McKee K, O'Dell S, Schmidt SD, Tran L, Yang Z, Druz A, Luongo TS, Moquin S, Srivatsan S, Yang Y, Zhang B, Zheng A, Pancera M, Kirys T, Georgiev IS, Gindin T, Peng HP, Yang AS; NISC Comparative Sequencing Program; Mullikin JC, Gray MD, Stamatatos L, Burton DR, Koff WC, Cohen MS, Haynes BF, Casazza JP, Connors M, Corti D, Lanzavecchia A, Sattentau QJ, Weiss RA, West AP Jr, Bjorkman PJ, Scheid JF, Nussenzweig MC, Shapiro L, Mascola JR, Kwong PD. Zhou T, et al. Among authors: acharya p. Cell. 2015 Jun 4;161(6):1280-92. doi: 10.1016/j.cell.2015.05.007. Epub 2015 May 21. Cell. 2015. PMID: 26004070 Free PMC article.
Crystal structure, conformational fixation and entry-related interactions of mature ligand-free HIV-1 Env.
Kwon YD, Pancera M, Acharya P, Georgiev IS, Crooks ET, Gorman J, Joyce MG, Guttman M, Ma X, Narpala S, Soto C, Terry DS, Yang Y, Zhou T, Ahlsen G, Bailer RT, Chambers M, Chuang GY, Doria-Rose NA, Druz A, Hallen MA, Harned A, Kirys T, Louder MK, O'Dell S, Ofek G, Osawa K, Prabhakaran M, Sastry M, Stewart-Jones GB, Stuckey J, Thomas PV, Tittley T, Williams C, Zhang B, Zhao H, Zhou Z, Donald BR, Lee LK, Zolla-Pazner S, Baxa U, Schön A, Freire E, Shapiro L, Lee KK, Arthos J, Munro JB, Blanchard SC, Mothes W, Binley JM, McDermott AB, Mascola JR, Kwong PD. Kwon YD, et al. Among authors: acharya p. Nat Struct Mol Biol. 2015 Jul;22(7):522-31. doi: 10.1038/nsmb.3051. Epub 2015 Jun 22. Nat Struct Mol Biol. 2015. PMID: 26098315 Free PMC article.
Quaternary contact in the initial interaction of CD4 with the HIV-1 envelope trimer.
Liu Q, Acharya P, Dolan MA, Zhang P, Guzzo C, Lu J, Kwon A, Gururani D, Miao H, Bylund T, Chuang GY, Druz A, Zhou T, Rice WJ, Wigge C, Carragher B, Potter CS, Kwong PD, Lusso P. Liu Q, et al. Among authors: acharya p. Nat Struct Mol Biol. 2017 Apr;24(4):370-378. doi: 10.1038/nsmb.3382. Epub 2017 Feb 20. Nat Struct Mol Biol. 2017. PMID: 28218750 Free PMC article.
Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.
LaBranche CC, Henderson R, Hsu A, Behrens S, Chen X, Zhou T, Wiehe K, Saunders KO, Alam SM, Bonsignori M, Borgnia MJ, Sattentau QJ, Eaton A, Greene K, Gao H, Liao HX, Williams WB, Peacock J, Tang H, Perez LG, Edwards RJ, Kepler TB, Korber BT, Kwong PD, Mascola JR, Acharya P, Haynes BF, Montefiori DC. LaBranche CC, et al. Among authors: acharya p. PLoS Pathog. 2019 Sep 17;15(9):e1008026. doi: 10.1371/journal.ppat.1008026. eCollection 2019 Sep. PLoS Pathog. 2019. PMID: 31527908 Free PMC article.
High-Throughput Mapping of B Cell Receptor Sequences to Antigen Specificity.
Setliff I, Shiakolas AR, Pilewski KA, Murji AA, Mapengo RE, Janowska K, Richardson S, Oosthuysen C, Raju N, Ronsard L, Kanekiyo M, Qin JS, Kramer KJ, Greenplate AR, McDonnell WJ, Graham BS, Connors M, Lingwood D, Acharya P, Morris L, Georgiev IS. Setliff I, et al. Among authors: acharya p. Cell. 2019 Dec 12;179(7):1636-1646.e15. doi: 10.1016/j.cell.2019.11.003. Epub 2019 Nov 28. Cell. 2019. PMID: 31787378 Free PMC article.
Correction: Neutralization-guided design of HIV-1 envelope trimers with high affinity for the unmutated common ancestor of CH235 lineage CD4bs broadly neutralizing antibodies.
LaBranche CC, Henderson R, Hsu A, Behrens S, Chen X, Zhou T, Wiehe K, Saunders KO, Alam SM, Bonsignori M, Borgnia MJ, Sattentau QJ, Eaton A, Greene K, Gao H, Liao HX, Williams WB, Peacock J, Tang H, Perez LG, Edwards RJ, Kepler TB, Korber BT, Kwong PD, Mascola JR, Acharya P, Haynes BF, Montefiori DC. LaBranche CC, et al. Among authors: acharya p. PLoS Pathog. 2019 Dec 2;15(12):e1008200. doi: 10.1371/journal.ppat.1008200. eCollection 2019 Dec. PLoS Pathog. 2019. PMID: 31790514 Free PMC article.
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation.
Saunders KO, Wiehe K, Tian M, Acharya P, Bradley T, Alam SM, Go EP, Scearce R, Sutherland L, Henderson R, Hsu AL, Borgnia MJ, Chen H, Lu X, Wu NR, Watts B, Jiang C, Easterhoff D, Cheng HL, McGovern K, Waddicor P, Chapdelaine-Williams A, Eaton A, Zhang J, Rountree W, Verkoczy L, Tomai M, Lewis MG, Desaire HR, Edwards RJ, Cain DW, Bonsignori M, Montefiori D, Alt FW, Haynes BF. Saunders KO, et al. Among authors: acharya p. Science. 2019 Dec 6;366(6470):eaay7199. doi: 10.1126/science.aay7199. Science. 2019. PMID: 31806786 Free PMC article.
Disruption of the HIV-1 Envelope allosteric network blocks CD4-induced rearrangements.
Henderson R, Lu M, Zhou Y, Mu Z, Parks R, Han Q, Hsu AL, Carter E, Blanchard SC, Edwards RJ, Wiehe K, Saunders KO, Borgnia MJ, Bartesaghi A, Mothes W, Haynes BF, Acharya P, Munir Alam S. Henderson R, et al. Among authors: acharya p. Nat Commun. 2020 Jan 24;11(1):520. doi: 10.1038/s41467-019-14196-w. Nat Commun. 2020. PMID: 31980614 Free PMC article.
620 results