Acharya K - Search Results

1

Identification of a glycan cluster in gp120 essential for irreversible HIV-1 lytic inactivation by a lectin-based recombinantly engineered protein conjugate.

Parajuli B, Acharya K, Nangarlia A, Zhang S, Parajuli B, Dick A, Ngo B, Abrams CF, Chaiken I. Parajuli B, et al. Among authors: acharya k. Biochem J. 2020 Nov 13;477(21):4263-4280. doi: 10.1042/BCJ20200495. Biochem J. 2020. PMID: 33057580

2

Lytic Inactivation of Human Immunodeficiency Virus by Dual Engagement of gp120 and gp41 Domains in the Virus Env Protein Trimer.

Parajuli B, Acharya K, Yu R, Ngo B, Rashad AA, Abrams CF, Chaiken IM. Parajuli B, et al. Among authors: acharya k. Biochemistry. 2016 Nov 8;55(44):6100-6114. doi: 10.1021/acs.biochem.6b00570. Epub 2016 Oct 27. Biochemistry. 2016. PMID: 27731975 Free PMC article.

3

Restricted HIV-1 Env glycan engagement by lectin-reengineered DAVEI protein chimera is sufficient for lytic inactivation of the virus.

Parajuli B, Acharya K, Bach HC, Parajuli B, Zhang S, Smith AB 3rd, Abrams CF, Chaiken I. Parajuli B, et al. Among authors: acharya k. Biochem J. 2018 Mar 9;475(5):931-957. doi: 10.1042/BCJ20170662. Biochem J. 2018. PMID: 29343613 Free PMC article.

4

Computational Evaluation of HIV-1 gp120 Conformations of Soluble Trimeric gp140 Structures as Targets for de Novo Docking of First- and Second-Generation Small-Molecule CD4 Mimics.

Moraca F, Acharya K, Melillo B, Smith AB 3rd, Chaiken I, Abrams CF. Moraca F, et al. Among authors: acharya k. J Chem Inf Model. 2016 Oct 24;56(10):2069-2079. doi: 10.1021/acs.jcim.6b00393. Epub 2016 Sep 26. J Chem Inf Model. 2016. PMID: 27602436 Free PMC article.

5

Recognition of HIV-inactivating peptide triazoles by the recombinant soluble Env trimer, BG505 SOSIP.664.

Acharya K, Rashad AA, Moraca F, Klasse PJ, Moore JP, Abrams C, Chaiken I. Acharya K, et al. Proteins. 2017 May;85(5):843-851. doi: 10.1002/prot.25238. Epub 2017 Mar 11. Proteins. 2017. PMID: 28056499 Free PMC article.

6

Bifunctional Chimera That Coordinately Targets Human Immunodeficiency Virus 1 Envelope gp120 and the Host-Cell CCR5 Coreceptor at the Virus-Cell Interface.

Rashad AA, Song LR, Holmes AP, Acharya K, Zhang S, Wang ZL, Gary E, Xie X, Pirrone V, Kutzler MA, Long YQ, Chaiken I. Rashad AA, et al. Among authors: acharya k. J Med Chem. 2018 Jun 14;61(11):5020-5033. doi: 10.1021/acs.jmedchem.8b00477. Epub 2018 Jun 1. J Med Chem. 2018. PMID: 29767965 Free PMC article.

7

Metastable HIV-1 Surface Protein Env Sensitizes Cell Membranes to Transformation and Poration by Dual-Acting Virucidal Entry Inhibitors.

Ang CG, Hossain MA, Rajpara M, Bach H, Acharya K, Dick A, Rashad AA, Kutzler M, Abrams CF, Chaiken I. Ang CG, et al. Among authors: acharya k. Biochemistry. 2020 Feb 18;59(6):818-828. doi: 10.1021/acs.biochem.9b01008. Epub 2020 Jan 28. Biochemistry. 2020. PMID: 31942789 Free PMC article.

8

Chemical optimization of macrocyclic HIV-1 inactivators for improving potency and increasing the structural diversity at the triazole ring.

Rashad AA, Acharya K, Haftl A, Aneja R, Dick A, Holmes AP, Chaiken I. Rashad AA, et al. Among authors: acharya k. Org Biomol Chem. 2017 Sep 26;15(37):7770-7782. doi: 10.1039/c7ob01448a. Org Biomol Chem. 2017. PMID: 28770939 Free PMC article.

9

To vaccinate or not against highly pathogenic avian influenza?

Acharya KP, Phuyal S. Acharya KP, et al. Lancet Microbe. 2024 May 15:S2666-5247(24)00107-1. doi: 10.1016/S2666-5247(24)00107-1. Online ahead of print. Lancet Microbe. 2024. PMID: 38761814 Free article. No abstract available.

10

A multicenter matched-cohort analysis of gastroschisis outcomes in infants born before 32 weeks gestation.

Pugh CP, Zaniletti I, Miquel-Verges F, Nghiem-Rao TH, Downey LC, Hightower H, Grover T, Murthy K, Riddle S, Acharya K; Children’s Hospitals Neonatal Consortium Gastroschisis Focus Group. Pugh CP, et al. Among authors: acharya k. J Perinatol. 2024 May 14. doi: 10.1038/s41372-024-01974-8. Online ahead of print. J Perinatol. 2024. PMID: 38744936

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