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Identification of Anti-Influenza A Compounds Inhibiting the Viral Non-Structural Protein 1 (NS1) Using a Type I Interferon-Driven Screening Strategy.
Marsili G, Acchioni C, Remoli AL, Amatore D, Sgarbanti R, De Angelis M, Orsatti R, Acchioni M, Astolfi A, Iraci N, Puzelli S, Facchini M, Perrotti E, Cecchetti V, Sabatini S, Superti F, Agamennone M, Barreca ML, Hiscott J, Nencioni L, Sgarbanti M. Marsili G, et al. Among authors: acchioni c. Int J Mol Sci. 2023 Jun 22;24(13):10495. doi: 10.3390/ijms241310495. Int J Mol Sci. 2023. PMID: 37445672 Free PMC article.
IκB kinase ε targets interferon regulatory factor 1 in activated T lymphocytes.
Sgarbanti M, Marsili G, Remoli AL, Stellacci E, Mai A, Rotili D, Perrotti E, Acchioni C, Orsatti R, Iraci N, Ferrari M, Borsetti A, Hiscott J, Battistini A. Sgarbanti M, et al. Among authors: acchioni c. Mol Cell Biol. 2014 Mar;34(6):1054-65. doi: 10.1128/MCB.01161-13. Epub 2014 Jan 6. Mol Cell Biol. 2014. PMID: 24396068 Free PMC article.
Type I IFN--a blunt spear in fighting HIV-1 infection.
Acchioni C, Marsili G, Perrotti E, Remoli AL, Sgarbanti M, Battistini A. Acchioni C, et al. Cytokine Growth Factor Rev. 2015 Apr;26(2):143-58. doi: 10.1016/j.cytogfr.2014.10.004. Epub 2014 Oct 30. Cytokine Growth Factor Rev. 2015. PMID: 25466629 Review.
Alternate NF-κB-Independent Signaling Reactivation of Latent HIV-1 Provirus.
Acchioni C, Remoli AL, Marsili G, Acchioni M, Nardolillo I, Orsatti R, Farcomeni S, Palermo E, Perrotti E, Barreca ML, Sabatini S, Sandini S, Parolin C, Lin R, Borsetti A, Hiscott J, Sgarbanti M. Acchioni C, et al. J Virol. 2019 Aug 28;93(18):e00495-19. doi: 10.1128/JVI.00495-19. Print 2019 Sep 15. J Virol. 2019. PMID: 31243131 Free PMC article.
A cellular screening platform, stably expressing DENV2 NS5, defines a novel anti-DENV mechanism of action of Apigenin based on STAT2 activation.
Acchioni C, Acchioni M, Mancini F, Amendola A, Marsili G, Tirelli V, Gwee CP, Chan KW, Sandini S, Bisbocci M, Mysara M, ElHefnawi M, Sanchez M, Venturi G, Barreca ML, Manfroni G, Bresciani A, Vasudevan SG, Sgarbanti M. Acchioni C, et al. Virology. 2023 Jun;583:1-13. doi: 10.1016/j.virol.2023.03.016. Epub 2023 Apr 5. Virology. 2023. PMID: 37060797 Free article.
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