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Fusarium verticillioides NAT1 (FDB2) N-malonyltransferase is structurally, functionally and phylogenetically distinct from its N-acetyltransferase (NAT) homologues.
Karagianni EP, Kontomina E, Lowe ED, Athanasopoulos K, Papanikolaou G, Garefalaki V, Kotseli V, Zaliou S, Grimaud T, Arvaniti K, Tsatiri MA, Fakis G, Glenn AE, Roversi P, Abuhammad A, Ryan A, Sim RB, Sim E, Boukouvala S. Karagianni EP, et al. Among authors: abuhammad a. FEBS J. 2023 May;290(9):2412-2436. doi: 10.1111/febs.16642. Epub 2022 Oct 18. FEBS J. 2023. PMID: 36178468 Free article.
Role of tyrosine 131 in the active site of paAzoR1, an azoreductase with specificity for the inflammatory bowel disease prodrug balsalazide.
Wang CJ, Laurieri N, Abuhammad A, Lowe E, Westwood I, Ryan A, Sim E. Wang CJ, et al. Among authors: abuhammad a. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Jan 1;66(Pt 1):2-7. doi: 10.1107/S1744309109044741. Epub 2009 Dec 25. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010. PMID: 20057057 Free PMC article.
Piperidinols that show anti-tubercular activity as inhibitors of arylamine N-acetyltransferase: an essential enzyme for mycobacterial survival inside macrophages.
Abuhammad A, Fullam E, Lowe ED, Staunton D, Kawamura A, Westwood IM, Bhakta S, Garner AC, Wilson DL, Seden PT, Davies SG, Russell AJ, Garman EF, Sim E. Abuhammad A, et al. PLoS One. 2012;7(12):e52790. doi: 10.1371/journal.pone.0052790. Epub 2012 Dec 28. PLoS One. 2012. PMID: 23285185 Free PMC article.
36 results