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YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors.
Stachelek GC, Peterson-Roth E, Liu Y, Fernandez RJ 3rd, Pike LR, Qian JM, Abriola L, Hoyer D, Hungerford W, Merkel J, Glazer PM. Stachelek GC, et al. Among authors: abriola l. Mol Cancer Res. 2015 Oct;13(10):1389-97. doi: 10.1158/1541-7786.MCR-15-0036. Epub 2015 Jun 26. Mol Cancer Res. 2015. PMID: 26116172 Free PMC article.
Phosphorylated WNK kinase networks in recoded bacteria recapitulate physiological function.
Schiapparelli P, Pirman NL, Mohler K, Miranda-Herrera PA, Zarco N, Kilic O, Miller C, Shah SR, Rogulina S, Hungerford W, Abriola L, Hoyer D, Turk BE, Guerrero-Cázares H, Isaacs FJ, Quiñones-Hinojosa A, Levchenko A, Rinehart J. Schiapparelli P, et al. Among authors: abriola l. Cell Rep. 2021 Jul 20;36(3):109416. doi: 10.1016/j.celrep.2021.109416. Cell Rep. 2021. PMID: 34289367 Free PMC article.
An allosteric site on MKP5 reveals a strategy for small-molecule inhibition.
Gannam ZTK, Min K, Shillingford SR, Zhang L, Herrington J, Abriola L, Gareiss PC, Pantouris G, Tzouvelekis A, Kaminski N, Zhang X, Yu J, Jamali H, Ellman JA, Lolis E, Anderson KS, Bennett AM. Gannam ZTK, et al. Among authors: abriola l. Sci Signal. 2020 Aug 25;13(646):eaba3043. doi: 10.1126/scisignal.aba3043. Sci Signal. 2020. PMID: 32843541 Free PMC article.
Engineered cardiac tissue model of restrictive cardiomyopathy for drug discovery.
Wang BZ, Nash TR, Zhang X, Rao J, Abriola L, Kim Y, Zakharov S, Kim M, Luo LJ, Morsink M, Liu B, Lock RI, Fleischer S, Tamargo MA, Bohnen M, Welch CL, Chung WK, Marx SO, Surovtseva YV, Vunjak-Novakovic G, Fine BM. Wang BZ, et al. Among authors: abriola l. Cell Rep Med. 2023 Mar 21;4(3):100976. doi: 10.1016/j.xcrm.2023.100976. Epub 2023 Mar 14. Cell Rep Med. 2023. PMID: 36921598 Free PMC article.
80 results