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Novel roles of androgen receptor, epidermal growth factor receptor, TP53, regulatory RNAs, NF-kappa-B, chromosomal translocations, neutrophil associated gelatinase, and matrix metalloproteinase-9 in prostate cancer and prostate cancer stem cells.
Chappell WH, Abrams SL, Lertpiriyapong K, Fitzgerald TL, Martelli AM, Cocco L, Rakus D, Gizak A, Terrian D, Steelman LS, McCubrey JA. Chappell WH, et al. Among authors: abrams sl. Adv Biol Regul. 2016 Jan;60:64-87. doi: 10.1016/j.jbior.2015.10.001. Epub 2015 Oct 9. Adv Biol Regul. 2016. PMID: 26525204 Review.
Metformin influences drug sensitivity in pancreatic cancer cells.
Candido S, Abrams SL, Steelman L, Lertpiriyapong K, Martelli AM, Cocco L, Ratti S, Follo MY, Murata RM, Rosalen PL, Lombardi P, Montalto G, Cervello M, Gizak A, Rakus D, Suh PG, Libra M, McCubrey JA. Candido S, et al. Among authors: abrams sl. Adv Biol Regul. 2018 May;68:13-30. doi: 10.1016/j.jbior.2018.02.002. Epub 2018 Feb 12. Adv Biol Regul. 2018. PMID: 29482945
Introduction of WT-TP53 into pancreatic cancer cells alters sensitivity to chemotherapeutic drugs, targeted therapeutics and nutraceuticals.
Abrams SL, Lertpiriyapong K, Yang LV, Martelli AM, Cocco L, Ratti S, Falasca M, Murata RM, Rosalen PL, Lombardi P, Libra M, Candido S, Montalto G, Cervello M, Steelman LS, McCubrey JA. Abrams SL, et al. Adv Biol Regul. 2018 Aug;69:16-34. doi: 10.1016/j.jbior.2018.06.002. Epub 2018 Jun 28. Adv Biol Regul. 2018. PMID: 29980405
Effects of the MDM-2 inhibitor Nutlin-3a on PDAC cells containing and lacking WT-TP53 on sensitivity to chemotherapy, signal transduction inhibitors and nutraceuticals.
Candido S, Abrams SL, Steelman LS, Lertpiriyapong K, Martelli AM, Cocco L, Ratti S, Follo MY, Murata RM, Rosalen PL, Bueno-Silva B, de Alencar SM, Lombardi P, Mao W, Montalto G, Cervello M, Rakus D, Gizak A, Lin HL, Libra M, Akula SM, McCubrey JA. Candido S, et al. Among authors: abrams sl. Adv Biol Regul. 2019 May;72:22-40. doi: 10.1016/j.jbior.2019.03.002. Epub 2019 Mar 15. Adv Biol Regul. 2019. PMID: 30898612
Abilities of β-Estradiol to interact with chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals and alter the proliferation of pancreatic cancer cells.
Akula SM, Candido S, Abrams SL, Steelman LS, Lertpiriyapong K, Cocco L, Ramazzotti G, Ratti S, Follo MY, Martelli AM, Murata RM, Rosalen PL, Bueno-Silva B, Matias de Alencar S, Falasca M, Montalto G, Cervello M, Notarbartolo M, Gizak A, Rakus D, Libra M, McCubrey JA. Akula SM, et al. Among authors: abrams sl. Adv Biol Regul. 2020 Jan;75:100672. doi: 10.1016/j.jbior.2019.100672. Epub 2019 Oct 18. Adv Biol Regul. 2020. PMID: 31685431
Targeting GSK3 and Associated Signaling Pathways Involved in Cancer.
Duda P, Akula SM, Abrams SL, Steelman LS, Martelli AM, Cocco L, Ratti S, Candido S, Libra M, Montalto G, Cervello M, Gizak A, Rakus D, McCubrey JA. Duda P, et al. Among authors: abrams sl. Cells. 2020 Apr 30;9(5):1110. doi: 10.3390/cells9051110. Cells. 2020. PMID: 32365809 Free PMC article. Review.
Influences of TP53 and the anti-aging DDR1 receptor in controlling Raf/MEK/ERK and PI3K/Akt expression and chemotherapeutic drug sensitivity in prostate cancer cell lines.
Chappell WH, Candido S, Abrams SL, Akula SM, Steelman LS, Martelli AM, Ratti S, Cocco L, Cervello M, Montalto G, Nicoletti F, Libra M, McCubrey JA. Chappell WH, et al. Among authors: abrams sl. Aging (Albany NY). 2020 Jun 3;12(11):10194-10210. doi: 10.18632/aging.103377. Epub 2020 Jun 3. Aging (Albany NY). 2020. PMID: 32492656 Free PMC article.
87 results