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Page 1
Screening of the Promising Direct Thrombin Inhibitors from Haematophagous Organisms. Part I: Recombinant Analogues and Their Antithrombotic Activity In Vitro.
Kostromina MA, Tukhovskaya EA, Shaykhutdinova ER, Slashcheva GA, Ismailova AM, Palikov VA, Palikova YA, Dyachenko IA, Kravchenko IN, Sadovnikova ES, Novikova NI, Perepechenova NA, Zayats EA, Abramchik YA, Lykoshin DD, Mamaev AN, Grigorieva EV, Momot AP, Murashev AN, Esipov RS. Kostromina MA, et al. Among authors: abramchik ya. Biomedicines. 2021 Dec 22;10(1):11. doi: 10.3390/biomedicines10010011. Biomedicines. 2021. PMID: 35052692 Free PMC article.
The comparative analysis of the properties and structures of purine nucleoside phosphorylases from thermophilic bacterium Thermus thermophilus HB27.
Timofeev VI, Fateev IV, Kostromina MA, Abramchik YA, Konstantinova ID, Volkov VV, Lykoshin DD, Mikheeva OO, Muravieva TI, Esipov RS, Kuranova IP. Timofeev VI, et al. Among authors: abramchik ya. J Biomol Struct Dyn. 2022 May;40(8):3626-3641. doi: 10.1080/07391102.2020.1848628. Epub 2020 Nov 23. J Biomol Struct Dyn. 2022. PMID: 33225840
Multi-Enzymatic Cascades in the Synthesis of Modified Nucleosides: Comparison of the Thermophilic and Mesophilic Pathways.
Fateev IV, Kostromina MA, Abramchik YA, Eletskaya BZ, Mikheeva OO, Lukoshin DD, Zayats EA, Berzina MY, Dorofeeva EV, Paramonov AS, Kayushin AL, Konstantinova ID, Esipov RS. Fateev IV, et al. Among authors: abramchik ya. Biomolecules. 2021 Apr 16;11(4):586. doi: 10.3390/biom11040586. Biomolecules. 2021. PMID: 33923608 Free PMC article.
Crystal structure of Escherichia coli purine nucleoside phosphorylase in complex with 7-deazahypoxanthine.
Timofeev VI, Zhukhlistova NE, Abramchik YA, Fateev II, Kostromina MA, Muravieva TI, Esipov RS, Kuranova IP. Timofeev VI, et al. Among authors: abramchik ya. Acta Crystallogr F Struct Biol Commun. 2018 Jun 1;74(Pt 6):355-362. doi: 10.1107/S2053230X18006337. Epub 2018 May 23. Acta Crystallogr F Struct Biol Commun. 2018. PMID: 29870020 Free PMC article.
Unified Methodology for the Primary Preclinical In Vivo Screening of New Anticoagulant Pharmaceutical Agents from Hematophagous Organisms.
Kostromina MA, Tukhovskaya EA, Shaykhutdinova ER, Palikova YA, Palikov VA, Slashcheva GA, Ismailova AM, Kravchenko IN, Dyachenko IA, Zayats EA, Abramchik YA, Murashev AN, Esipov RS. Kostromina MA, et al. Among authors: abramchik ya. Int J Mol Sci. 2024 Apr 3;25(7):3986. doi: 10.3390/ijms25073986. Int J Mol Sci. 2024. PMID: 38612796 Free PMC article.
Rational Mutagenesis in the Lid Domain of Ribokinase from E. coli Results in an Order of Magnitude Increase in Activity towards D-arabinose.
Zayats EA, Fateev IV, Kostromina MA, Abramchik YA, Lykoshin DD, Yurovskaya DO, Timofeev VI, Berzina MY, Eletskaya BZ, Konstantinova ID, Esipov RS. Zayats EA, et al. Among authors: abramchik ya. Int J Mol Sci. 2022 Oct 19;23(20):12540. doi: 10.3390/ijms232012540. Int J Mol Sci. 2022. PMID: 36293391 Free PMC article.
Synthesis of 2-chloropurine ribosides with chiral amino acid amides at C6 and their evaluation as A1 adenosine receptor agonists.
Berzina MY, Eletskaya BZ, Kayushin AL, Dorofeeva EV, Lutonina OI, Fateev IV, Paramonov AS, Kostromina MA, Zayats EA, Abramchik YA, Maltsev DV, Naumenko LV, Taran AS, Yakovlev DS, Spasov AA, Miroshnikov AI, Esipov RS, Konstantinova ID. Berzina MY, et al. Among authors: abramchik ya. Bioorg Chem. 2022 Sep;126:105878. doi: 10.1016/j.bioorg.2022.105878. Epub 2022 May 18. Bioorg Chem. 2022. PMID: 35660725