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Small RNAs control sodium channel expression, nociceptor excitability, and pain thresholds.
Zhao J, Lee MC, Momin A, Cendan CM, Shepherd ST, Baker MD, Asante C, Bee L, Bethry A, Perkins JR, Nassar MA, Abrahamsen B, Dickenson A, Cobb BS, Merkenschlager M, Wood JN. Zhao J, et al. Among authors: abrahamsen b. J Neurosci. 2010 Aug 11;30(32):10860-71. doi: 10.1523/JNEUROSCI.1980-10.2010. J Neurosci. 2010. PMID: 20702715 Free PMC article.
Ion channel activities implicated in pathological pain.
Wood JN, Abrahamsen B, Baker MD, Boorman JD, Donier E, Drew LJ, Nassar MA, Okuse K, Seereeram A, Stirling CL, Zhao J. Wood JN, et al. Among authors: abrahamsen b. Novartis Found Symp. 2004;261:32-40; discussion 40-54. Novartis Found Symp. 2004. PMID: 15469043
muO-conotoxin MrVIB selectively blocks Nav1.8 sensory neuron specific sodium channels and chronic pain behavior without motor deficits.
Ekberg J, Jayamanne A, Vaughan CW, Aslan S, Thomas L, Mould J, Drinkwater R, Baker MD, Abrahamsen B, Wood JN, Adams DJ, Christie MJ, Lewis RJ. Ekberg J, et al. Among authors: abrahamsen b. Proc Natl Acad Sci U S A. 2006 Nov 7;103(45):17030-5. doi: 10.1073/pnas.0601819103. Epub 2006 Oct 31. Proc Natl Acad Sci U S A. 2006. PMID: 17077153 Free PMC article.
A sensory subpopulation depends on vesicular glutamate transporter 2 for mechanical pain, and together with substance P, inflammatory pain.
Lagerström MC, Rogoz K, Abrahamsen B, Lind AL, Olund C, Smith C, Mendez JA, Wallén-Mackenzie Å, Wood JN, Kullander K. Lagerström MC, et al. Among authors: abrahamsen b. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5789-94. doi: 10.1073/pnas.1013602108. Epub 2011 Mar 17. Proc Natl Acad Sci U S A. 2011. PMID: 21415372 Free PMC article.
VGLUT2-dependent sensory neurons in the TRPV1 population regulate pain and itch.
Lagerström MC, Rogoz K, Abrahamsen B, Persson E, Reinius B, Nordenankar K, Olund C, Smith C, Mendez JA, Chen ZF, Wood JN, Wallén-Mackenzie A, Kullander K. Lagerström MC, et al. Among authors: abrahamsen b. Neuron. 2010 Nov 4;68(3):529-42. doi: 10.1016/j.neuron.2010.09.016. Neuron. 2010. PMID: 21040852 Free PMC article.
338 results