Abouzayed A - Search Results

1

Half-life extension via ADB-fusion leads to higher tumor uptake of an affibody-drug conjugate compared to PAS- and XTENylation.

Zhang J, Bodenko V, Larkina M, Bezverkhniaia E, Xu T, Liao Y, Abouzayed A, Plotnikov E, Tretyakova M, Yuldasheva F, Belousov MV, Orlova A, Tolmachev V, Gräslund T, Vorobyeva A. Zhang J, et al. Among authors: abouzayed a. J Control Release. 2024 Apr 30:S0168-3659(24)00280-3. doi: 10.1016/j.jconrel.2024.04.051. Online ahead of print. J Control Release. 2024. PMID: 38697314

2

Two Novel [⁶⁸Ga]Ga-Labeled Radiotracers Based on Metabolically Stable [Sar¹¹]RM26 Antagonistic Peptide for Diagnostic Positron Emission Tomography Imaging of GRPR-Positive Prostate Cancer.

Kanellopoulos P, Bezverkhniaia E, Abouzayed A, Rosenström U, Tolmachev V, Orlova A. Kanellopoulos P, et al. Among authors: abouzayed a. ACS Omega. 2024 Apr 10;9(16):18608-18616. doi: 10.1021/acsomega.4c01348. eCollection 2024 Apr 23. ACS Omega. 2024. PMID: 38680331 Free PMC article.

3

GRPR-Antagonists Carrying DOTAGA-Chelator via Positively Charged Linkers: Perspectives for Prostate Cancer Theranostics.

Obeid K, Kanellopoulos P, Abouzayed A, Mattsson A, Tolmachev V, Nock BA, Maina T, Orlova A. Obeid K, et al. Among authors: abouzayed a. Pharmaceutics. 2024 Apr 8;16(4):513. doi: 10.3390/pharmaceutics16040513. Pharmaceutics. 2024. PMID: 38675174 Free PMC article.

4

Preclinical evaluation of new GRPR-antagonists with improved metabolic stability for radiotheranostic use in oncology.

Kanellopoulos P, Mattsson A, Abouzayed A, Obeid K, Nock BA, Tolmachev V, Maina T, Orlova A. Kanellopoulos P, et al. Among authors: abouzayed a. EJNMMI Radiopharm Chem. 2024 Feb 16;9(1):13. doi: 10.1186/s41181-024-00242-6. EJNMMI Radiopharm Chem. 2024. PMID: 38366299 Free PMC article.

5

Preclinical Evaluation of a Novel High-Affinity Radioligand [^99mTc]Tc-BQ0413 Targeting Prostate-Specific Membrane Antigen (PSMA).

Bezverkhniaia E, Kanellopoulos P, Abouzayed A, Larkina M, Oroujeni M, Vorobyeva A, Rosenström U, Tolmachev V, Orlova A. Bezverkhniaia E, et al. Among authors: abouzayed a. Int J Mol Sci. 2023 Dec 12;24(24):17391. doi: 10.3390/ijms242417391. Int J Mol Sci. 2023. PMID: 38139219 Free PMC article.

6

¹⁷⁷Lu-labeled PSMA targeting therapeutic with optimized linker for treatment of disseminated prostate cancer; evaluation of biodistribution and dosimetry.

Abouzayed A, Seitova K, Lundmark F, Bodenko V, Oroujeni M, Tolmachev V, Rosenström U, Orlova A. Abouzayed A, et al. Front Oncol. 2023 Sep 27;13:1221103. doi: 10.3389/fonc.2023.1221103. eCollection 2023. Front Oncol. 2023. PMID: 37829345 Free PMC article.

7

Preclinical Characterization of a Stabilized Gastrin-Releasing Peptide Receptor Antagonist for Targeted Cancer Theranostics.

Abouzayed A, Kanellopoulos P, Gorislav A, Tolmachev V, Maina T, Nock BA, Orlova A. Abouzayed A, et al. Biomolecules. 2023 Jul 14;13(7):1134. doi: 10.3390/biom13071134. Biomolecules. 2023. PMID: 37509170 Free PMC article.

8

Co-injection of anti-HER2 antibody Trastuzumab does not increase efficacy of [¹⁷⁷Lu]Lu-PSMA-617 therapy in an animal model of prostate cancer.

Abouzayed A, Zedan W, Altai M, Strand J, Örbom A. Abouzayed A, et al. Am J Nucl Med Mol Imaging. 2023 Jun 25;13(3):107-117. eCollection 2023. Am J Nucl Med Mol Imaging. 2023. PMID: 37457328 Free PMC article.

9

The GRPR Antagonist [^99mTc]Tc-maSSS-PEG₂-RM26 towards Phase I Clinical Trial: Kit Preparation, Characterization and Toxicity.

Abouzayed A, Borin J, Lundmark F, Rybina A, Hober S, Zelchan R, Tolmachev V, Chernov V, Orlova A. Abouzayed A, et al. Diagnostics (Basel). 2023 May 2;13(9):1611. doi: 10.3390/diagnostics13091611. Diagnostics (Basel). 2023. PMID: 37175001 Free PMC article.

10

Phase I Trial of [^99mTc]Tc-maSSS-PEG₂-RM26, a Bombesin Analogue Antagonistic to Gastrin-Releasing Peptide Receptors (GRPRs), for SPECT Imaging of GRPR Expression in Malignant Tumors.

Chernov V, Rybina A, Zelchan R, Medvedeva A, Bragina O, Lushnikova N, Doroshenko A, Usynin E, Tashireva L, Vtorushin S, Abouzayed A, Rinne SS, Sörensen J, Tolmachev V, Orlova A. Chernov V, et al. Among authors: abouzayed a. Cancers (Basel). 2023 Mar 7;15(6):1631. doi: 10.3390/cancers15061631. Cancers (Basel). 2023. PMID: 36980517 Free PMC article.

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