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The cGAS-STING pathway drives type I IFN immunopathology in COVID-19.
Domizio JD, Gulen MF, Saidoune F, Thacker VV, Yatim A, Sharma K, Nass T, Guenova E, Schaller M, Conrad C, Goepfert C, de Leval L, Garnier CV, Berezowska S, Dubois A, Gilliet M, Ablasser A. Domizio JD, et al. Among authors: ablasser a. Nature. 2022 Mar;603(7899):145-151. doi: 10.1038/s41586-022-04421-w. Epub 2022 Jan 19. Nature. 2022. PMID: 35045565 Free PMC article.
Structural mechanism of cytosolic DNA sensing by cGAS.
Civril F, Deimling T, de Oliveira Mann CC, Ablasser A, Moldt M, Witte G, Hornung V, Hopfner KP. Civril F, et al. Among authors: ablasser a. Nature. 2013 Jun 20;498(7454):332-7. doi: 10.1038/nature12305. Epub 2013 May 30. Nature. 2013. PMID: 23722159 Free PMC article.
Inside Job: Viruses Transfer cGAMP between Cells.
Gulen MF, Ablasser A. Gulen MF, et al. Among authors: ablasser a. Cell Host Microbe. 2015 Sep 9;18(3):263-5. doi: 10.1016/j.chom.2015.08.008. Cell Host Microbe. 2015. PMID: 26355209 Free article.
ReGLUation of cGAS.
Ablasser A. Ablasser A. Nat Immunol. 2016 Apr;17(4):347-9. doi: 10.1038/ni.3397. Nat Immunol. 2016. PMID: 27002833 No abstract available.
The role of cGAS in innate immunity and beyond.
Ablasser A, Gulen MF. Ablasser A, et al. J Mol Med (Berl). 2016 Oct;94(10):1085-1093. doi: 10.1007/s00109-016-1423-2. Epub 2016 May 6. J Mol Med (Berl). 2016. PMID: 27154323 Review.
60 results