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Targeting STING with covalent small-molecule inhibitors.
Haag SM, Gulen MF, Reymond L, Gibelin A, Abrami L, Decout A, Heymann M, van der Goot FG, Turcatti G, Behrendt R, Ablasser A. Haag SM, et al. Among authors: ablasser a. Nature. 2018 Jul;559(7713):269-273. doi: 10.1038/s41586-018-0287-8. Epub 2018 Jul 4. Nature. 2018. PMID: 29973723
Inside Job: Viruses Transfer cGAMP between Cells.
Gulen MF, Ablasser A. Gulen MF, et al. Among authors: ablasser a. Cell Host Microbe. 2015 Sep 9;18(3):263-5. doi: 10.1016/j.chom.2015.08.008. Cell Host Microbe. 2015. PMID: 26355209 Free article.
Signalling strength determines proapoptotic functions of STING.
Gulen MF, Koch U, Haag SM, Schuler F, Apetoh L, Villunger A, Radtke F, Ablasser A. Gulen MF, et al. Among authors: ablasser a. Nat Commun. 2017 Sep 5;8(1):427. doi: 10.1038/s41467-017-00573-w. Nat Commun. 2017. PMID: 28874664 Free PMC article.
Human cGAS Has a Slightly Different Taste for dsDNA.
Decout A, Ablasser A. Decout A, et al. Among authors: ablasser a. Immunity. 2018 Aug 21;49(2):206-208. doi: 10.1016/j.immuni.2018.08.005. Immunity. 2018. PMID: 30134199 Free article.
Intracellular bacteria engage a STING-TBK1-MVB12b pathway to enable paracrine cGAS-STING signalling.
Nandakumar R, Tschismarov R, Meissner F, Prabakaran T, Krissanaprasit A, Farahani E, Zhang BC, Assil S, Martin A, Bertrams W, Holm CK, Ablasser A, Klause T, Thomsen MK, Schmeck B, Howard KA, Henry T, Gothelf KV, Decker T, Paludan SR. Nandakumar R, et al. Among authors: ablasser a. Nat Microbiol. 2019 Apr;4(4):701-713. doi: 10.1038/s41564-019-0367-z. Epub 2019 Feb 25. Nat Microbiol. 2019. PMID: 30804548 Free PMC article.
Virology: Poxins Soothe the STING.
Decout A, Ablasser A. Decout A, et al. Among authors: ablasser a. Curr Biol. 2019 May 6;29(9):R332-R334. doi: 10.1016/j.cub.2019.03.031. Curr Biol. 2019. PMID: 31063727 Free article.
60 results