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Reactive astrocytes promote proteostasis in Huntington's disease through the JAK2-STAT3 pathway.
Abjean L, Ben Haim L, Riquelme-Perez M, Gipchtein P, Derbois C, Palomares MA, Petit F, Hérard AS, Gaillard MC, Guillermier M, Gaudin-Guérif M, Aurégan G, Sagar N, Héry C, Dufour N, Robil N, Kabani M, Melki R, De la Grange P, Bemelmans AP, Bonvento G, Deleuze JF, Hantraye P, Flament J, Bonnet E, Brohard S, Olaso R, Brouillet E, Carrillo-de Sauvage MA, Escartin C. Abjean L, et al. Brain. 2023 Jan 5;146(1):149-166. doi: 10.1093/brain/awac068. Brain. 2023. PMID: 35298632
Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease.
Ceyzériat K, Ben Haim L, Denizot A, Pommier D, Matos M, Guillemaud O, Palomares MA, Abjean L, Petit F, Gipchtein P, Gaillard MC, Guillermier M, Bernier S, Gaudin M, Aurégan G, Joséphine C, Déchamps N, Veran J, Langlais V, Cambon K, Bemelmans AP, Baijer J, Bonvento G, Dhenain M, Deleuze JF, Oliet SHR, Brouillet E, Hantraye P, Carrillo-de Sauvage MA, Olaso R, Panatier A, Escartin C. Ceyzériat K, et al. Among authors: abjean l. Acta Neuropathol Commun. 2018 Oct 16;6(1):104. doi: 10.1186/s40478-018-0606-1. Acta Neuropathol Commun. 2018. PMID: 30322407 Free PMC article.
A seeding-based neuronal model of tau aggregation for use in drug discovery.
Amorim IS, Challal S, Cistarelli L, Dorval T, Abjean L, Touzard M, Arbez N, François A, Panayi F, Jeggo R, Cecon E, Oishi A, Dam J, Jockers R, Machado P. Amorim IS, et al. Among authors: abjean l. PLoS One. 2023 Apr 4;18(4):e0283941. doi: 10.1371/journal.pone.0283941. eCollection 2023. PLoS One. 2023. PMID: 37014877 Free PMC article.