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Page 1
MEK1/2 regulate normal BCR and ABL1 tumor-suppressor functions to dictate ATO response in TKI-resistant Ph+ leukemia.
Mazzera L, Abeltino M, Lombardi G, Cantoni AM, Jottini S, Corradi A, Ricca M, Rossetti E, Armando F, Peli A, Ferrari A, Martinelli G, Scupoli MT, Visco C, Bonifacio M, Ripamonti A, Gambacorti-Passerini C, Bonati A, Perris R, Lunghi P. Mazzera L, et al. Among authors: abeltino m. Leukemia. 2023 Aug;37(8):1671-1685. doi: 10.1038/s41375-023-01940-x. Epub 2023 Jun 29. Leukemia. 2023. PMID: 37386079 Free PMC article.
Functional interplay between NF-κB-inducing kinase and c-Abl kinases limits response to Aurora inhibitors in multiple myeloma.
Mazzera L, Abeltino M, Lombardi G, Cantoni AM, Ria R, Ricca M, Saltarella I, Naponelli V, Rizzi FMA, Perris R, Corradi A, Vacca A, Bonati A, Lunghi P. Mazzera L, et al. Among authors: abeltino m. Haematologica. 2019 Dec;104(12):2465-2481. doi: 10.3324/haematol.2018.208280. Epub 2019 Apr 4. Haematologica. 2019. PMID: 30948493 Free PMC article.
HOXB7 expression by myeloma cells regulates their pro-angiogenic properties in multiple myeloma patients.
Storti P, Donofrio G, Colla S, Airoldi I, Bolzoni M, Agnelli L, Abeltino M, Todoerti K, Lazzaretti M, Mancini C, Ribatti D, Bonomini S, Franceschi V, Pistoia V, Lisignoli G, Pedrazzini A, Cavicchi O, Neri A, Rizzoli V, Giuliani N. Storti P, et al. Among authors: abeltino m. Leukemia. 2011 Mar;25(3):527-37. doi: 10.1038/leu.2010.270. Epub 2010 Nov 23. Leukemia. 2011. PMID: 21183939 Free article.
The proapoptotic effect of zoledronic acid is independent of either the bone microenvironment or the intrinsic resistance to bortezomib of myeloma cells and is enhanced by the combination with arsenic trioxide.
Abeltino M, Bonomini S, Bolzoni M, Storti P, Colla S, Todoerti K, Agnelli L, Neri A, Rizzoli V, Giuliani N. Abeltino M, et al. Exp Hematol. 2011 Jan;39(1):55-65. doi: 10.1016/j.exphem.2010.10.005. Epub 2010 Oct 25. Exp Hematol. 2011. PMID: 20977926
Bone osteoblastic and mesenchymal stromal cells lack primarily tumoral features in multiple myeloma patients.
Giuliani N, Lisignoli G, Novara F, Storti P, Zaffaroni N, Villa R, Sammarelli G, Agnelli L, Todoerti K, Bernardo ME, Manferdini C, Colla S, Abeltino M, Bolzoni M, Rocci A, Gabusi E, Palumbo A, Zuffardi O, Neri A, Rizzoli V. Giuliani N, et al. Among authors: abeltino m. Leukemia. 2010 Jul;24(7):1368-70. doi: 10.1038/leu.2010.96. Epub 2010 May 20. Leukemia. 2010. PMID: 20485369 No abstract available.
Low bone marrow oxygen tension and hypoxia-inducible factor-1α overexpression characterize patients with multiple myeloma: role on the transcriptional and proangiogenic profiles of CD138(+) cells.
Colla S, Storti P, Donofrio G, Todoerti K, Bolzoni M, Lazzaretti M, Abeltino M, Ippolito L, Neri A, Ribatti D, Rizzoli V, Martella E, Giuliani N. Colla S, et al. Among authors: abeltino m. Leukemia. 2010 Nov;24(11):1967-70. doi: 10.1038/leu.2010.193. Epub 2010 Sep 2. Leukemia. 2010. PMID: 20811474 No abstract available.
Interleukin-27 acts as multifunctional antitumor agent in multiple myeloma.
Cocco C, Giuliani N, Di Carlo E, Ognio E, Storti P, Abeltino M, Sorrentino C, Ponzoni M, Ribatti D, Airoldi I. Cocco C, et al. Among authors: abeltino m. Clin Cancer Res. 2010 Aug 15;16(16):4188-97. doi: 10.1158/1078-0432.CCR-10-0173. Epub 2010 Jun 29. Clin Cancer Res. 2010. PMID: 20587591
Distinct transcriptional profiles characterize bone microenvironment mesenchymal cells rather than osteoblasts in relationship with multiple myeloma bone disease.
Todoerti K, Lisignoli G, Storti P, Agnelli L, Novara F, Manferdini C, Codeluppi K, Colla S, Crugnola M, Abeltino M, Bolzoni M, Sgobba V, Facchini A, Lambertenghi-Deliliers G, Zuffardi O, Rizzoli V, Neri A, Giuliani N. Todoerti K, et al. Among authors: abeltino m. Exp Hematol. 2010 Feb;38(2):141-53. doi: 10.1016/j.exphem.2009.11.009. Epub 2009 Dec 4. Exp Hematol. 2010. PMID: 19963035 Free article.