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Spidroin N-terminal domain forms amyloid-like fibril based hydrogels and provides a protein immobilization platform.
Arndt T, Jaudzems K, Shilkova O, Francis J, Johansson M, Laity PR, Sahin C, Chatterjee U, Kronqvist N, Barajas-Ledesma E, Kumar R, Chen G, Strömberg R, Abelein A, Langton M, Landreh M, Barth A, Holland C, Johansson J, Rising A. Arndt T, et al. Among authors: abelein a. Nat Commun. 2022 Aug 15;13(1):4695. doi: 10.1038/s41467-022-32093-7. Nat Commun. 2022. PMID: 35970823 Free PMC article.
Bri2 BRICHOS client specificity and chaperone activity are governed by assembly state.
Chen G, Abelein A, Nilsson HE, Leppert A, Andrade-Talavera Y, Tambaro S, Hemmingsson L, Roshan F, Landreh M, Biverstål H, Koeck PJB, Presto J, Hebert H, Fisahn A, Johansson J. Chen G, et al. Among authors: abelein a. Nat Commun. 2017 Dec 12;8(1):2081. doi: 10.1038/s41467-017-02056-4. Nat Commun. 2017. PMID: 29234026 Free PMC article.
High intracellular stability of the spidroin N-terminal domain in spite of abundant amyloidogenic segments revealed by in-cell hydrogen/deuterium exchange mass spectrometry.
Kaldmäe M, Leppert A, Chen G, Sarr M, Sahin C, Nordling K, Kronqvist N, Gonzalvo-Ulla M, Fritz N, Abelein A, Laίn S, Biverstål H, Jörnvall H, Lane DP, Rising A, Johansson J, Landreh M. Kaldmäe M, et al. Among authors: abelein a. FEBS J. 2020 Jul;287(13):2823-2833. doi: 10.1111/febs.15169. Epub 2019 Dec 20. FEBS J. 2020. PMID: 31815338 Free PMC article.
Functionalization of amyloid fibrils via the Bri2 BRICHOS domain.
Biverstål H, Kumar R, Schellhaus AK, Sarr M, Dantuma NP, Abelein A, Johansson J. Biverstål H, et al. Among authors: abelein a. Sci Rep. 2020 Dec 10;10(1):21765. doi: 10.1038/s41598-020-78732-1. Sci Rep. 2020. PMID: 33303867 Free PMC article.
The synthesis and characterization of Bri2 BRICHOS coated magnetic particles and their application to protein fishing: Identification of novel binding proteins.
Tigro H, Kronqvist N, Abelein A, Galan-Acosta L, Chen G, Landreh M, Lyashkov A, Aon MA, Ferrucci L, Shimmo R, Johansson J, Moaddel R. Tigro H, et al. Among authors: abelein a. J Pharm Biomed Anal. 2021 May 10;198:113996. doi: 10.1016/j.jpba.2021.113996. Epub 2021 Feb 26. J Pharm Biomed Anal. 2021. PMID: 33690096 Free PMC article.
34 results