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Energy-preserving effects of IGF-1 antagonize starvation-induced cardiac autophagy.
Troncoso R, Vicencio JM, Parra V, Nemchenko A, Kawashima Y, Del Campo A, Toro B, Battiprolu PK, Aranguiz P, Chiong M, Yakar S, Gillette TG, Hill JA, Abel ED, Leroith D, Lavandero S. Troncoso R, et al. Among authors: abel ed. Cardiovasc Res. 2012 Feb 1;93(2):320-9. doi: 10.1093/cvr/cvr321. Epub 2011 Dec 1. Cardiovasc Res. 2012. PMID: 22135164 Free PMC article.
Insulin stimulates mitochondrial fusion and function in cardiomyocytes via the Akt-mTOR-NFκB-Opa-1 signaling pathway.
Parra V, Verdejo HE, Iglewski M, Del Campo A, Troncoso R, Jones D, Zhu Y, Kuzmicic J, Pennanen C, Lopez-Crisosto C, Jaña F, Ferreira J, Noguera E, Chiong M, Bernlohr DA, Klip A, Hill JA, Rothermel BA, Abel ED, Zorzano A, Lavandero S. Parra V, et al. Among authors: abel ed. Diabetes. 2014 Jan;63(1):75-88. doi: 10.2337/db13-0340. Epub 2013 Sep 5. Diabetes. 2014. PMID: 24009260 Free PMC article.
Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.
Riehle C, Wende AR, Zhu Y, Oliveira KJ, Pereira RO, Jaishy BP, Bevins J, Valdez S, Noh J, Kim BJ, Moreira AB, Weatherford ET, Manivel R, Rawlings TA, Rech M, White MF, Abel ED. Riehle C, et al. Among authors: abel ed. Mol Cell Biol. 2014 Sep 15;34(18):3450-60. doi: 10.1128/MCB.00426-14. Epub 2014 Jul 7. Mol Cell Biol. 2014. PMID: 25002528 Free PMC article.
Insulin regulation of myocardial autophagy.
Riehle C, Abel ED. Riehle C, et al. Among authors: abel ed. Circ J. 2014;78(11):2569-76. doi: 10.1253/circj.cj-14-1080. Epub 2014 Oct 20. Circ J. 2014. PMID: 25327953 Free PMC article. Review.
287 results