Abegg D - Search Results

1

Artemisinin inhibits NRas palmitoylation by targeting the protein acyltransferase ZDHHC6.

Qiu N, Abegg D, Guidi M, Gilmore K, Seeberger PH, Adibekian A. Qiu N, et al. Among authors: abegg d. Cell Chem Biol. 2022 Mar 17;29(3):530-537.e7. doi: 10.1016/j.chembiol.2021.07.012. Epub 2021 Aug 5. Cell Chem Biol. 2022. PMID: 34358442 Free article.

2

Identification of Covalent Bromodomain Binders through DNA Display of Small Molecules.

Daguer JP, Zambaldo C, Abegg D, Barluenga S, Tallant C, Müller S, Adibekian A, Winssinger N. Daguer JP, et al. Among authors: abegg d. Angew Chem Int Ed Engl. 2015 May 11;54(20):6057-61. doi: 10.1002/anie.201412276. Epub 2015 Mar 13. Angew Chem Int Ed Engl. 2015. PMID: 25772490

3

Proteome-Wide Profiling of Targets of Cysteine reactive Small Molecules by Using Ethynyl Benziodoxolone Reagents.

Abegg D, Frei R, Cerato L, Prasad Hari D, Wang C, Waser J, Adibekian A. Abegg D, et al. Angew Chem Int Ed Engl. 2015 Sep 7;54(37):10852-7. doi: 10.1002/anie.201505641. Epub 2015 Jul 24. Angew Chem Int Ed Engl. 2015. PMID: 26211368

4

Chemoproteomics-Enabled Discovery of a Potent and Selective Inhibitor of the DNA Repair Protein MGMT.

Wang C, Abegg D, Hoch DG, Adibekian A. Wang C, et al. Among authors: abegg d. Angew Chem Int Ed Engl. 2016 Feb 18;55(8):2911-5. doi: 10.1002/anie.201511301. Epub 2016 Jan 22. Angew Chem Int Ed Engl. 2016. PMID: 26798972

5

Divergent synthesis and identification of the cellular targets of deoxyelephantopins.

Lagoutte R, Serba C, Abegg D, Hoch DG, Adibekian A, Winssinger N. Lagoutte R, et al. Among authors: abegg d. Nat Commun. 2016 Aug 19;7:12470. doi: 10.1038/ncomms12470. Nat Commun. 2016. PMID: 27539788 Free PMC article.

6

Strained Cyclic Disulfides Enable Cellular Uptake by Reacting with the Transferrin Receptor.

Abegg D, Gasparini G, Hoch DG, Shuster A, Bartolami E, Matile S, Adibekian A. Abegg D, et al. J Am Chem Soc. 2017 Jan 11;139(1):231-238. doi: 10.1021/jacs.6b09643. Epub 2016 Dec 21. J Am Chem Soc. 2017. PMID: 28001050

7

Epidithiodiketopiperazines: Strain-Promoted Thiol-Mediated Cellular Uptake at the Highest Tension.

Zong L, Bartolami E, Abegg D, Adibekian A, Sakai N, Matile S. Zong L, et al. Among authors: abegg d. ACS Cent Sci. 2017 May 24;3(5):449-453. doi: 10.1021/acscentsci.7b00080. Epub 2017 Apr 6. ACS Cent Sci. 2017. PMID: 28573207 Free PMC article.

8

Cysteine-specific Chemical Proteomics: From Target Identification to Drug Discovery.

Hoch DG, Abegg D, Wang C, Shuster A, Adibekian A. Hoch DG, et al. Among authors: abegg d. Chimia (Aarau). 2016 Nov 30;70(11):764-767. doi: 10.2533/chimia.2016.764. Chimia (Aarau). 2016. PMID: 28661335 Free article. Review.

9

The SAGA complex, together with transcription factors and the endocytic protein Rvs167p, coordinates the reprofiling of gene expression in response to changes in sterol composition in Saccharomyces cerevisiae.

Dewhurst-Maridor G, Abegg D, David FPA, Rougemont J, Scott CC, Adibekian A, Riezman H. Dewhurst-Maridor G, et al. Among authors: abegg d. Mol Biol Cell. 2017 Oct 1;28(20):2637-2649. doi: 10.1091/mbc.E17-03-0169. Epub 2017 Aug 2. Mol Biol Cell. 2017. PMID: 28768829 Free PMC article.

10

Cysteine-reactive probes and their use in chemical proteomics.

Hoch DG , Abegg D , Adibekian A . Hoch DG , et al. Among authors: abegg d. Chem Commun (Camb). 2018 May 1;54(36):4501-4512. doi: 10.1039/c8cc01485j. Chem Commun (Camb). 2018. PMID: 29645055

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