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Scaffold Repurposing Reveals New Nanomolar Phosphodiesterase Type 5 (PDE5) Inhibitors Based on Pyridopyrazinone Scaffold: Investigation of In Vitro and In Silico Properties.
Amin KM, El-Badry OM, Abdel Rahman DE, Abdellattif MH, Abourehab MAS, El-Maghrabey MH, Elsaid FG, El Hamd MA, Elkamhawy A, Ammar UM. Amin KM, et al. Among authors: abdellattif mh. Pharmaceutics. 2022 Sep 15;14(9):1954. doi: 10.3390/pharmaceutics14091954. Pharmaceutics. 2022. PMID: 36145702 Free PMC article.
Discovery of 3,4-dichloro-N-(1H-indol-5-yl)benzamide: A highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability profile and neuroprotective action.
Elkamhawy A, Kim HJ, Elsherbeny MH, Paik S, Park JH, Gotina L, Abdellattif MH, Gouda NA, Cho J, Lee K, Nim Pae A, Park KD, Roh EJ. Elkamhawy A, et al. Among authors: abdellattif mh. Bioorg Chem. 2021 Nov;116:105352. doi: 10.1016/j.bioorg.2021.105352. Epub 2021 Sep 11. Bioorg Chem. 2021. PMID: 34562673
2-(3-Bromophenyl)-8-fluoroquinazoline-4-carboxylic Acid as a Novel and Selective Aurora A Kinase Inhibitory Lead with Apoptosis Properties: Design, Synthesis, In Vitro and In Silico Biological Evaluation.
Elsherbeny MH, Ammar UM, Abdellattif MH, Abourehab MAS, Abdeen A, Ibrahim SF, Abdelrahaman D, Mady W, Roh EJ, Elkamhawy A. Elsherbeny MH, et al. Among authors: abdellattif mh. Life (Basel). 2022 Jun 10;12(6):876. doi: 10.3390/life12060876. Life (Basel). 2022. PMID: 35743907 Free PMC article.
Novel Hybrid Indole-Based Caffeic Acid Amide Derivatives as Potent Free Radical Scavenging Agents: Rational Design, Synthesis, Spectroscopic Characterization, In Silico and In Vitro Investigations.
Elkamhawy A, Oh NK, Gouda NA, Abdellattif MH, Alshammari SO, Abourehab MAS, Alshammari QA, Belal A, Kim M, Al-Karmalawy AA, Lee K. Elkamhawy A, et al. Among authors: abdellattif mh. Metabolites. 2023 Jan 17;13(2):141. doi: 10.3390/metabo13020141. Metabolites. 2023. PMID: 36837759 Free PMC article.
67 results