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Synthesis, biological evaluation, docking study and ulcerogenicity profiling of some novel quinoline-2-carboxamides as dual COXs/LOX inhibitors endowed with anti-inflammatory activity.
Abdelrahman MH, Youssif BGM, Abdelgawad MA, Abdelazeem AH, Ibrahim HM, Moustafa AEGA, Treamblu L, Bukhari SNA. Abdelrahman MH, et al. Among authors: abdelazeem ah. Eur J Med Chem. 2017 Feb 15;127:972-985. doi: 10.1016/j.ejmech.2016.11.006. Epub 2016 Nov 5. Eur J Med Chem. 2017. PMID: 27837994
Design, synthesis, mechanistic and histopathological studies of small-molecules of novel indole-2-carboxamides and pyrazino[1,2-a]indol-1(2H)-ones as potential anticancer agents effecting the reactive oxygen species production.
Youssif BGM, Abdelrahman MH, Abdelazeem AH, Abdelgawad MA, Ibrahim HM, Salem OIA, Mohamed MFA, Treambleau L, Bukhari SNA. Youssif BGM, et al. Among authors: abdelazeem ah. Eur J Med Chem. 2018 Feb 25;146:260-273. doi: 10.1016/j.ejmech.2018.01.042. Epub 2018 Jan 31. Eur J Med Chem. 2018. PMID: 29407956
New Sulfamethoxazole Derivatives as Selective Carbonic Anhydrase IX and XII Inhibitors: Design, Synthesis, Cytotoxic Activity and Molecular Modeling.
Abdelgawad MA, Bukhari SNA, Musa A, Elmowafy M, Elkomy MH, Nayl AA, El-Ghorab AH, Alsohaimi IH, Abdel-Bakky MS, Althobaiti IO, Altaleb HA, Omar HA, Abdelazeem AH, Zaki MA, Shaker ME, Elshemy HAH. Abdelgawad MA, et al. Among authors: abdelazeem ah. Pharmaceuticals (Basel). 2022 Sep 10;15(9):1134. doi: 10.3390/ph15091134. Pharmaceuticals (Basel). 2022. PMID: 36145355 Free PMC article.
46 results