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Bile acid biosynthesis in Smith-Lemli-Opitz syndrome bypassing cholesterol: Potential importance of pathway intermediates.
Abdel-Khalik J, Hearn T, Dickson AL, Crick PJ, Yutuc E, Austin-Muttitt K, Bigger BW, Morris AA, Shackleton CH, Clayton PT, Iida T, Sircar R, Rohatgi R, Marschall HU, Sjövall J, Björkhem I, Mullins JGL, Griffiths WJ, Wang Y. Abdel-Khalik J, et al. J Steroid Biochem Mol Biol. 2021 Feb;206:105794. doi: 10.1016/j.jsbmb.2020.105794. Epub 2020 Nov 24. J Steroid Biochem Mol Biol. 2021. PMID: 33246156 Free PMC article.
New methods for analysis of oxysterols and related compounds by LC-MS.
Griffiths WJ, Abdel-Khalik J, Crick PJ, Yutuc E, Wang Y. Griffiths WJ, et al. J Steroid Biochem Mol Biol. 2016 Sep;162:4-26. doi: 10.1016/j.jsbmb.2015.11.017. Epub 2015 Nov 27. J Steroid Biochem Mol Biol. 2016. PMID: 26639636 Free article. Review.
Sterols and oxysterols in plasma from Smith-Lemli-Opitz syndrome patients.
Griffiths WJ, Abdel-Khalik J, Crick PJ, Ogundare M, Shackleton CH, Tuschl K, Kwok MK, Bigger BW, Morris AA, Honda A, Xu L, Porter NA, Björkhem I, Clayton PT, Wang Y. Griffiths WJ, et al. J Steroid Biochem Mol Biol. 2017 May;169:77-87. doi: 10.1016/j.jsbmb.2016.03.018. Epub 2016 Mar 11. J Steroid Biochem Mol Biol. 2017. PMID: 26976653 Free PMC article.
Cholesterolomics: An update.
Griffiths WJ, Abdel-Khalik J, Yutuc E, Morgan AH, Gilmore I, Hearn T, Wang Y. Griffiths WJ, et al. Anal Biochem. 2017 May 1;524:56-67. doi: 10.1016/j.ab.2017.01.009. Epub 2017 Jan 10. Anal Biochem. 2017. PMID: 28087213 Free PMC article. Review.
Identification of unusual oxysterols and bile acids with 7-oxo or 3β,5α,6β-trihydroxy functions in human plasma by charge-tagging mass spectrometry with multistage fragmentation.
Griffiths WJ, Gilmore I, Yutuc E, Abdel-Khalik J, Crick PJ, Hearn T, Dickson A, Bigger BW, Wu TH, Goenka A, Ghosh A, Jones SA, Wang Y. Griffiths WJ, et al. Among authors: abdel khalik j. J Lipid Res. 2018 Jun;59(6):1058-1070. doi: 10.1194/jlr.D083246. Epub 2018 Apr 6. J Lipid Res. 2018. PMID: 29626102 Free PMC article.
Additional pathways of sterol metabolism: Evidence from analysis of Cyp27a1-/- mouse brain and plasma.
Griffiths WJ, Crick PJ, Meljon A, Theofilopoulos S, Abdel-Khalik J, Yutuc E, Parker JE, Kelly DE, Kelly SL, Arenas E, Wang Y. Griffiths WJ, et al. Among authors: abdel khalik j. Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Feb;1864(2):191-211. doi: 10.1016/j.bbalip.2018.11.006. Epub 2018 Nov 22. Biochim Biophys Acta Mol Cell Biol Lipids. 2019. PMID: 30471425 Free PMC article.
Formation and metabolism of oxysterols and cholestenoic acids found in the mouse circulation: Lessons learnt from deuterium-enrichment experiments and the CYP46A1 transgenic mouse.
Crick PJ, Yutuc E, Abdel-Khalik J, Saeed A, Betsholtz C, Genove G, Björkhem I, Wang Y, Griffiths WJ. Crick PJ, et al. Among authors: abdel khalik j. J Steroid Biochem Mol Biol. 2019 Dec;195:105475. doi: 10.1016/j.jsbmb.2019.105475. Epub 2019 Sep 18. J Steroid Biochem Mol Biol. 2019. PMID: 31541728 Free PMC article.
23 results