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Discovery of novel benzofuran-based derivatives as acetylcholinesterase inhibitors for the treatment of Alzheimer's disease: Design, synthesis, biological evaluation, molecular docking and 3D-QSAR investigation.
Abd El-Karim SS, Anwar MM, Ahmed NS, Syam YM, Elseginy SA, Aly HF, Younis EA, Khalil WKB, Ahmed KA, Mohammed FF, Rizk M. Abd El-Karim SS, et al. Eur J Med Chem. 2023 Nov 15;260:115766. doi: 10.1016/j.ejmech.2023.115766. Epub 2023 Aug 28. Eur J Med Chem. 2023. PMID: 37678141
Synthesis and biological evaluation of new derivatives of thieno-thiazole and dihydrothiazolo-thiazole scaffolds integrated with a pyrazoline nucleus as anticancer and multi-targeting kinase inhibitors.
Othman IMM, Alamshany ZM, Tashkandi NY, Gad-Elkareem MAM, Abd El-Karim SS, Nossier ES. Othman IMM, et al. Among authors: abd el karim ss. RSC Adv. 2021 Dec 22;12(1):561-577. doi: 10.1039/d1ra08055e. eCollection 2021 Dec 20. RSC Adv. 2021. PMID: 35424523 Free PMC article.
Discovery of New Coumarin-Based Lead with Potential Anticancer, CDK4 Inhibition and Selective Radiotheranostic Effect: Synthesis, 2D & 3D QSAR, Molecular Dynamics, In Vitro Cytotoxicity, Radioiodination, and Biodistribution Studies.
Sarhan MO, Abd El-Karim SS, Anwar MM, Gouda RH, Zaghary WA, Khedr MA. Sarhan MO, et al. Among authors: abd el karim ss. Molecules. 2021 Apr 14;26(8):2273. doi: 10.3390/molecules26082273. Molecules. 2021. PMID: 33919867 Free PMC article.
22 results