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Patient- and xenograft-derived organoids recapitulate pediatric brain tumor features and patient treatments.
Lago C, Federico A, Leva G, Mack NL, Schwalm B, Ballabio C, Gianesello M, Abballe L, Giovannoni I, Reddel S, Rossi S, Leone N, Carai A, Mastronuzzi A, Bisio A, Soldano A, Quintarelli C, Locatelli F, Kool M, Miele E, Tiberi L. Lago C, et al. Among authors: abballe l. EMBO Mol Med. 2023 Dec 7;15(12):e18199. doi: 10.15252/emmm.202318199. Epub 2023 Nov 30. EMBO Mol Med. 2023. PMID: 38037472 Free PMC article.
Downregulation of miR-326 and its host gene β-arrestin1 induces pro-survival activity of E2F1 and promotes medulloblastoma growth.
Miele E, Po A, Mastronuzzi A, Carai A, Besharat ZM, Pediconi N, Abballe L, Catanzaro G, Sabato C, De Smaele E, Canettieri G, Di Marcotullio L, Vacca A, Mai A, Levrero M, Pfister SM, Kool M, Giangaspero F, Locatelli F, Ferretti E. Miele E, et al. Among authors: abballe l. Mol Oncol. 2021 Feb;15(2):523-542. doi: 10.1002/1878-0261.12800. Epub 2020 Dec 31. Mol Oncol. 2021. PMID: 32920979 Free PMC article.
Targeting cancer stem cells in medulloblastoma by inhibiting AMBRA1 dual function in autophagy and STAT3 signalling.
Nazio F, Po A, Abballe L, Ballabio C, Diomedi Camassei F, Bordi M, Camera A, Caruso S, Caruana I, Pezzullo M, Ferraina C, Milletti G, Gianesello M, Reddel S, De Luca CD, Ceglie D, Marinelli S, Campello S, Papaleo E, Miele E, Cacchione A, Carai A, Vinci M, Velardi E, De Angelis B, Tiberi L, Quintarelli C, Mastronuzzi A, Ferretti E, Locatelli F, Cecconi F. Nazio F, et al. Among authors: abballe l. Acta Neuropathol. 2021 Sep;142(3):537-564. doi: 10.1007/s00401-021-02347-7. Epub 2021 Jul 24. Acta Neuropathol. 2021. PMID: 34302498 Free PMC article.
β-arrestin1-mediated acetylation of Gli1 regulates Hedgehog/Gli signaling and modulates self-renewal of SHH medulloblastoma cancer stem cells.
Miele E, Po A, Begalli F, Antonucci L, Mastronuzzi A, Marras CE, Carai A, Cucchi D, Abballe L, Besharat ZM, Catanzaro G, Infante P, Di Marcotullio L, Canettieri G, De Smaele E, Screpanti I, Locatelli F, Ferretti E. Miele E, et al. Among authors: abballe l. BMC Cancer. 2017 Jul 17;17(1):488. doi: 10.1186/s12885-017-3477-0. BMC Cancer. 2017. PMID: 28716052 Free PMC article.
Adoptive Immunotherapy Using PRAME-Specific T Cells in Medulloblastoma.
Orlando D, Miele E, De Angelis B, Guercio M, Boffa I, Sinibaldi M, Po A, Caruana I, Abballe L, Carai A, Caruso S, Camera A, Moseley A, Hagedoorn RS, Heemskerk MHM, Giangaspero F, Mastronuzzi A, Ferretti E, Locatelli F, Quintarelli C. Orlando D, et al. Among authors: abballe l. Cancer Res. 2018 Jun 15;78(12):3337-3349. doi: 10.1158/0008-5472.CAN-17-3140. Epub 2018 Apr 3. Cancer Res. 2018. PMID: 29615432
β-arrestin1-E2F1-ac axis regulates physiological apoptosis and cell cycle exit in cellular models of early postnatal cerebellum.
Abballe L, Alfano V, Antonacci C, Cefalo MG, Cacchione A, Del Baldo G, Pezzullo M, Po A, Moretti M, Mastronuzzi A, De Smaele E, Ferretti E, Locatelli F, Miele E. Abballe L, et al. Front Cell Dev Biol. 2023 Feb 27;11:990711. doi: 10.3389/fcell.2023.990711. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 36923256 Free PMC article.
32 results