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Persistent Polyfunctional Chimeric Antigen Receptor T Cells That Target Glypican 3 Eliminate Orthotopic Hepatocellular Carcinomas in Mice.
Li D, Li N, Zhang YF, Fu H, Feng M, Schneider D, Su L, Wu X, Zhou J, Mackay S, Kramer J, Duan Z, Yang H, Kolluri A, Hummer AM, Torres MB, Zhu H, Hall MD, Luo X, Chen J, Wang Q, Abate-Daga D, Dropulic B, Hewitt SM, Orentas RJ, Greten TF, Ho M. Li D, et al. Gastroenterology. 2020 Jun;158(8):2250-2265.e20. doi: 10.1053/j.gastro.2020.02.011. Epub 2020 Feb 12. Gastroenterology. 2020. PMID: 32060001 Free PMC article.
4-1BB enhancement of CAR T function requires NF-κB and TRAFs.
Li G, Boucher JC, Kotani H, Park K, Zhang Y, Shrestha B, Wang X, Guan L, Beatty N, Abate-Daga D, Davila ML. Li G, et al. JCI Insight. 2018 Sep 20;3(18):e121322. doi: 10.1172/jci.insight.121322. eCollection 2018 Sep 20. JCI Insight. 2018. PMID: 30232281 Free PMC article.
An immunoproteomic approach to characterize the CAR interactome and signalosome.
Ramello MC, Benzaïd I, Kuenzi BM, Lienlaf-Moreno M, Kandell WM, Santiago DN, Pabón-Saldaña M, Darville L, Fang B, Rix U, Yoder S, Berglund A, Koomen JM, Haura EB, Abate-Daga D. Ramello MC, et al. Sci Signal. 2019 Feb 12;12(568):eaap9777. doi: 10.1126/scisignal.aap9777. Sci Signal. 2019. PMID: 30755478 Free PMC article.
41 results