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Phenotypic, chemical and functional characterization of cyclic nucleotide phosphodiesterase 4 (PDE4) as a potential anthelmintic drug target.
Long T, Rojo-Arreola L, Shi D, El-Sakkary N, Jarnagin K, Rock F, Meewan M, Rascón AA Jr, Lin L, Cunningham KA, Lemieux GA, Podust L, Abagyan R, Ashrafi K, McKerrow JH, Caffrey CR. Long T, et al. Among authors: abagyan r. PLoS Negl Trop Dis. 2017 Jul 13;11(7):e0005680. doi: 10.1371/journal.pntd.0005680. eCollection 2017 Jul. PLoS Negl Trop Dis. 2017. PMID: 28704396 Free PMC article.
Structure-based approaches to antibiotic drug discovery.
Nicola G, Abagyan R. Nicola G, et al. Among authors: abagyan r. Curr Protoc Microbiol. 2009 Feb;Chapter 17:Unit17.2. doi: 10.1002/9780471729259.mc1702s12. Curr Protoc Microbiol. 2009. PMID: 19235149
Multi-targeting Drug Community Challenge.
Schlessinger A, Abagyan R, Carlson HA, Dang KK, Guinney J, Cagan RL. Schlessinger A, et al. Among authors: abagyan r. Cell Chem Biol. 2017 Dec 21;24(12):1434-1435. doi: 10.1016/j.chembiol.2017.12.006. Cell Chem Biol. 2017. PMID: 29272700 Free article. No abstract available.
Discovery of Triple Inhibitors of Both SARS-CoV-2 Proteases and Human Cathepsin L.
Meewan I, Kattoula J, Kattoula JY, Skinner D, Fajtová P, Giardini MA, Woodworth B, McKerrow JH, Lage de Siqueira-Neto J, O'Donoghue AJ, Abagyan R. Meewan I, et al. Among authors: abagyan r. Pharmaceuticals (Basel). 2022 Jun 13;15(6):744. doi: 10.3390/ph15060744. Pharmaceuticals (Basel). 2022. PMID: 35745663 Free PMC article.
343 results