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Page 1
Smad4 haploinsufficiency: a matter of dosage.
Alberici P, Gaspar C, Franken P, Gorski MM, de Vries I, Scott RJ, Ristimäki A, Aaltonen LA, Fodde R. Alberici P, et al. Among authors: aaltonen la. Pathogenetics. 2008 Nov 3;1(1):2. doi: 10.1186/1755-8417-1-2. Pathogenetics. 2008. PMID: 19014666 Free PMC article.
Multiple components of PKA and TGF-β pathways are mutated in pseudomyxoma peritonei.
Saarinen L, Nummela P, Thiel A, Lehtonen R, Järvinen P, Järvinen H, Aaltonen LA, Lepistö A, Hautaniemi S, Ristimäki A. Saarinen L, et al. Among authors: aaltonen la. PLoS One. 2017 Apr 20;12(4):e0174898. doi: 10.1371/journal.pone.0174898. eCollection 2017. PLoS One. 2017. PMID: 28426742 Free PMC article.
Unregulated smooth-muscle myosin in human intestinal neoplasia.
Alhopuro P, Phichith D, Tuupanen S, Sammalkorpi H, Nybondas M, Saharinen J, Robinson JP, Yang Z, Chen LQ, Orntoft T, Mecklin JP, Järvinen H, Eng C, Moeslein G, Shibata D, Houlston RS, Lucassen A, Tomlinson IP, Launonen V, Ristimäki A, Arango D, Karhu A, Sweeney HL, Aaltonen LA. Alhopuro P, et al. Among authors: aaltonen la. Proc Natl Acad Sci U S A. 2008 Apr 8;105(14):5513-8. doi: 10.1073/pnas.0801213105. Epub 2008 Apr 7. Proc Natl Acad Sci U S A. 2008. PMID: 18391202 Free PMC article.
Induction of cyclooxygenase-2 in a mouse model of Peutz-Jeghers polyposis.
Rossi DJ, Ylikorkala A, Korsisaari N, Salovaara R, Luukko K, Launonen V, Henkemeyer M, Ristimaki A, Aaltonen LA, Makela TP. Rossi DJ, et al. Among authors: aaltonen la. Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12327-32. doi: 10.1073/pnas.192301399. Epub 2002 Sep 6. Proc Natl Acad Sci U S A. 2002. PMID: 12218179 Free PMC article.
The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhanced Wnt signaling.
Tuupanen S, Turunen M, Lehtonen R, Hallikas O, Vanharanta S, Kivioja T, Björklund M, Wei G, Yan J, Niittymäki I, Mecklin JP, Järvinen H, Ristimäki A, Di-Bernardo M, East P, Carvajal-Carmona L, Houlston RS, Tomlinson I, Palin K, Ukkonen E, Karhu A, Taipale J, Aaltonen LA. Tuupanen S, et al. Among authors: aaltonen la. Nat Genet. 2009 Aug;41(8):885-90. doi: 10.1038/ng.406. Epub 2009 Jun 28. Nat Genet. 2009. PMID: 19561604
Exome-wide somatic mutation characterization of small bowel adenocarcinoma.
Hänninen UA, Katainen R, Tanskanen T, Plaketti RM, Laine R, Hamberg J, Ristimäki A, Pukkala E, Taipale M, Mecklin JP, Forsström LM, Pitkänen E, Palin K, Välimäki N, Mäkinen N, Aaltonen LA. Hänninen UA, et al. Among authors: aaltonen la. PLoS Genet. 2018 Mar 9;14(3):e1007200. doi: 10.1371/journal.pgen.1007200. eCollection 2018 Mar. PLoS Genet. 2018. PMID: 29522538 Free PMC article.
Human cell transformation by combined lineage conversion and oncogene expression.
Sahu B, Pihlajamaa P, Zhang K, Palin K, Ahonen S, Cervera A, Ristimäki A, Aaltonen LA, Hautaniemi S, Taipale J. Sahu B, et al. Among authors: aaltonen la. Oncogene. 2021 Sep;40(36):5533-5547. doi: 10.1038/s41388-021-01940-0. Epub 2021 Jul 23. Oncogene. 2021. PMID: 34302118 Free PMC article.
405 results