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Page 1
Characterization, Dynamics, and Mechanism of CXCR4 Antagonists on a Constitutively Active Mutant.
Rosenberg EM Jr, Harrison RES, Tsou LK, Drucker N, Humphries B, Rajasekaran D, Luker KE, Wu CH, Song JS, Wang CJ, Murphy JW, Cheng YC, Shia KS, Luker GD, Morikis D, Lolis EJ. Rosenberg EM Jr, et al. Cell Chem Biol. 2019 May 16;26(5):662-673.e7. doi: 10.1016/j.chembiol.2019.01.012. Epub 2019 Feb 28. Cell Chem Biol. 2019. PMID: 30827936 Free PMC article.
Nanosecond Dynamics Regulate the MIF-Induced Activity of CD74.
Pantouris G, Ho J, Shah D, Syed MA, Leng L, Bhandari V, Bucala R, Batista VS, Loria JP, Lolis EJ. Pantouris G, et al. Angew Chem Int Ed Engl. 2018 Jun 11;57(24):7116-7119. doi: 10.1002/anie.201803191. Epub 2018 May 9. Angew Chem Int Ed Engl. 2018. PMID: 29669180 Free PMC article.
Identification of an Arg-Leu-Arg tripeptide that contributes to the binding interface between the cytokine MIF and the chemokine receptor CXCR4.
Lacy M, Kontos C, Brandhofer M, Hille K, Gröning S, Sinitski D, Bourilhon P, Rosenberg E, Krammer C, Thavayogarajah T, Pantouris G, Bakou M, Weber C, Lolis E, Bernhagen J, Kapurniotu A. Lacy M, et al. Sci Rep. 2018 Mar 26;8(1):5171. doi: 10.1038/s41598-018-23554-5. Sci Rep. 2018. PMID: 29581527 Free PMC article.
Macrophage Migration Inhibitory Factor-CXCR4 Receptor Interactions: EVIDENCE FOR PARTIAL ALLOSTERIC AGONISM IN COMPARISON WITH CXCL12 CHEMOKINE.
Rajasekaran D, Gröning S, Schmitz C, Zierow S, Drucker N, Bakou M, Kohl K, Mertens A, Lue H, Weber C, Xiao A, Luker G, Kapurniotu A, Lolis E, Bernhagen J. Rajasekaran D, et al. J Biol Chem. 2016 Jul 22;291(30):15881-95. doi: 10.1074/jbc.M116.717751. Epub 2016 May 19. J Biol Chem. 2016. PMID: 27226569 Free PMC article.
19 results