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DUSP5-mediated inhibition of smooth muscle cell proliferation suppresses pulmonary hypertension and right ventricular hypertrophy.
Ferguson BS, Wennersten SA, Demos-Davies KM, Rubino M, Robinson EL, Cavasin MA, Stratton MS, Kidger AM, Hu T, Keyse SM, McKnight RA, Lane RH, Nozik ES, Weiser-Evans MCM, McKinsey TA. Ferguson BS, et al. Am J Physiol Heart Circ Physiol. 2021 Aug 1;321(2):H382-H389. doi: 10.1152/ajpheart.00115.2021. Epub 2021 Jun 18. Am J Physiol Heart Circ Physiol. 2021. PMID: 34142888 Free PMC article.
Gene trap mice reveal an essential function of dual specificity phosphatase Dusp16/MKP-7 in perinatal survival and regulation of Toll-like receptor (TLR)-induced cytokine production.
Niedzielska M, Bodendorfer B, Münch S, Eichner A, Derigs M, da Costa O, Schweizer A, Neff F, Nitschke L, Sparwasser T, Keyse SM, Lang R. Niedzielska M, et al. J Biol Chem. 2014 Jan 24;289(4):2112-26. doi: 10.1074/jbc.M113.535245. Epub 2013 Dec 5. J Biol Chem. 2014. PMID: 24311790 Free PMC article.
Phosphorylation of the kinase interaction motif in mitogen-activated protein (MAP) kinase phosphatase-4 mediates cross-talk between protein kinase A and MAP kinase signaling pathways.
Dickinson RJ, Delavaine L, Cejudo-Marín R, Stewart G, Staples CJ, Didmon MP, Trinidad AG, Alonso A, Pulido R, Keyse SM. Dickinson RJ, et al. J Biol Chem. 2011 Nov 4;286(44):38018-38026. doi: 10.1074/jbc.M111.255844. Epub 2011 Sep 9. J Biol Chem. 2011. PMID: 21908610 Free PMC article.