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Increasing the binding affinity of VEGFR-2 inhibitors by extending their hydrophobic interaction with the active site: Design, synthesis and biological evaluation of 1-substituted-4-(4-methoxybenzyl)phthalazine derivatives.
Eldehna WM, Abou-Seri SM, El Kerdawy AM, Ayyad RR, Hamdy AM, Ghabbour HA, Ali MM, Abou El Ella DA. Eldehna WM, et al. Eur J Med Chem. 2016 May 4;113:50-62. doi: 10.1016/j.ejmech.2016.02.029. Epub 2016 Feb 15. Eur J Med Chem. 2016. PMID: 26922228
Activity of chalcones derived from 2,4,5-trimethoxybenzaldehyde against Meloidogyne exigua and in silico interaction of one chalcone with a putative caffeic acid 3-O-methyltransferase from Meloidogyne incognita.
Nunes AS, Campos VP, Mascarello A, Stumpf TR, Chiaradia-Delatorre LD, Machado AR, Santos Júnior HM, Yunes RA, Nunes RJ, Oliveira DF. Nunes AS, et al. Exp Parasitol. 2013 Dec;135(4):661-8. doi: 10.1016/j.exppara.2013.10.003. Epub 2013 Oct 17. Exp Parasitol. 2013. PMID: 24140596
29 results