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Chemical conjugation of 2-hexadecynoic acid to C5-curcumin enhances its antibacterial activity against multi-drug resistant bacteria.
Sanabria-Ríos DJ, Rivera-Torres Y, Rosario J, Gutierrez R, Torres-García Y, Montano N, Ortíz-Soto G, Ríos-Olivares E, Rodríguez JW, Carballeira NM. Sanabria-Ríos DJ, et al. Bioorg Med Chem Lett. 2015 Nov 15;25(22):5067-71. doi: 10.1016/j.bmcl.2015.10.022. Epub 2015 Oct 14. Bioorg Med Chem Lett. 2015. PMID: 26483137 Free PMC article.
Synthesis of novel C5-curcuminoid-fatty acid conjugates and mechanistic investigation of their anticancer activity.
Sanabria-Ríos DJ, Rivera-Torres Y, Rosario J, Ríos C, Gutierrez R, Carballeira NM, Vélez C, Zayas B, Álvarez-Colón F, Ortiz-Soto G, Serrano V, Altieri-Rivera J, Ríos-Olivares E, Rodríguez JW. Sanabria-Ríos DJ, et al. Bioorg Med Chem Lett. 2015;25(10):2174-80. doi: 10.1016/j.bmcl.2015.03.065. Epub 2015 Mar 31. Bioorg Med Chem Lett. 2015. PMID: 25881826 Free PMC article.
Antibacterial activity of 2-alkynoic fatty acids against multidrug-resistant bacteria.
Sanabria-Ríos DJ, Rivera-Torres Y, Maldonado-Domínguez G, Domínguez I, Ríos C, Díaz D, Rodríguez JW, Altieri-Rivera JS, Ríos-Olivares E, Cintrón G, Montano N, Carballeira NM. Sanabria-Ríos DJ, et al. Chem Phys Lipids. 2014 Feb;178:84-91. doi: 10.1016/j.chemphyslip.2013.12.006. Epub 2013 Dec 21. Chem Phys Lipids. 2014. PMID: 24365283 Free PMC article.