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2021 4
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2024 9

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Tigilanol tiglate is an oncolytic small molecule that induces immunogenic cell death and enhances the response of both target and non-injected tumors to immune checkpoint blockade.
Cullen JK, Yap PY, Ferguson B, Bruce ZC, Koyama M, Handoko H, Hendrawan K, Simmons JL, Brooks KM, Johns J, Wilson ES, de Souza MMA, Broit N, Stewart P, Shelley D, McMahon T, Ogbourne SM, Nguyen TH, Lim YC, Pagani A, Appendino G, Gordon VA, Reddell PW, Boyle GM, Parsons PG. Cullen JK, et al. J Immunother Cancer. 2024 Apr 24;12(4):e006602. doi: 10.1136/jitc-2022-006602. J Immunother Cancer. 2024. PMID: 38658031 Free PMC article.
A general platform for targeting MHC-II antigens via a single loop.
Du H, Liu J, Jude KM, Yang X, Li Y, Bell B, Yang H, Kassardjian A, Mobedi A, Parekh U, Sperberg RAP, Julien JP, Mellins ED, Garcia KC, Huang PS. Du H, et al. bioRxiv [Preprint]. 2024 Jan 30:2024.01.26.577489. doi: 10.1101/2024.01.26.577489. bioRxiv. 2024. PMID: 38352315 Free PMC article. Preprint.
Prevention of respiratory virus transmission by resident memory CD8+ T cells.
Uddbäck I, Michalets SE, Saha A, Mattingly C, Kost KN, Williams ME, Lawrence LA, Hicks SL, Lowen AC, Ahmed H, Thomsen AR, Russell CJ, Scharer CD, Boss JM, Koelle K, Antia R, Christensen JP, Kohlmeier JE. Uddbäck I, et al. Nature. 2024 Feb;626(7998):392-400. doi: 10.1038/s41586-023-06937-1. Epub 2023 Dec 12. Nature. 2024. PMID: 38086420
Kruppel-like factor 2+ CD4 T cells avert microbiota-induced intestinal inflammation.
Shao TY, Jiang TT, Stevens J, Russi AE, Troutman TD, Bernieh A, Pham G, Erickson JJ, Eshleman EM, Alenghat T, Jameson SC, Hogquist KA, Weaver CT, Haslam DB, Deshmukh H, Way SS. Shao TY, et al. Cell Rep. 2023 Nov 28;42(11):113323. doi: 10.1016/j.celrep.2023.113323. Epub 2023 Oct 26. Cell Rep. 2023. PMID: 37889750 Free PMC article.
40 results