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Hepatocyte apical bulkheads provide a mechanical means to oppose bile pressure.
J Cell Biol. 2023 Apr 3;222(4):e202208002. doi: 10.1083/jcb.202208002. Epub 2023 Jan 30.
J Cell Biol. 2023.
PMID: 36716168
Free PMC article.
Anisotropic expansion of hepatocyte lumina enforced by apical bulkheads.
Belicova L, Repnik U, Delpierre J, Gralinska E, Seifert S, Valenzuela JI, Morales-Navarrete HA, Franke C, Räägel H, Shcherbinina E, Prikazchikova T, Koteliansky V, Vingron M, Kalaidzidis YL, Zatsepin T, Zerial M.
Belicova L, et al.
J Cell Biol. 2021 Oct 4;220(10):e202103003. doi: 10.1083/jcb.202103003. Epub 2021 Jul 30.
J Cell Biol. 2021.
PMID: 34328499
Free PMC article.
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Quantification of nematic cell polarity in three-dimensional tissues.
Scholich A, Syga S, Morales-Navarrete H, Segovia-Miranda F, Nonaka H, Meyer K, de Back W, Brusch L, Kalaidzidis Y, Zerial M, Jülicher F, Friedrich BM.
Scholich A, et al.
PLoS Comput Biol. 2020 Dec 10;16(12):e1008412. doi: 10.1371/journal.pcbi.1008412. eCollection 2020 Dec.
PLoS Comput Biol. 2020.
PMID: 33301446
Free PMC article.
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Three-dimensional spatially resolved geometrical and functional models of human liver tissue reveal new aspects of NAFLD progression.
Segovia-Miranda F, Morales-Navarrete H, Kücken M, Moser V, Seifert S, Repnik U, Rost F, Brosch M, Hendricks A, Hinz S, Röcken C, Lütjohann D, Kalaidzidis Y, Schafmayer C, Brusch L, Hampe J, Zerial M.
Segovia-Miranda F, et al.
Nat Med. 2019 Dec;25(12):1885-1893. doi: 10.1038/s41591-019-0660-7. Epub 2019 Dec 2.
Nat Med. 2019.
PMID: 31792455
Free PMC article.
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A Predictive 3D Multi-Scale Model of Biliary Fluid Dynamics in the Liver Lobule.
Meyer K, Ostrenko O, Bourantas G, Morales-Navarrete H, Porat-Shliom N, Segovia-Miranda F, Nonaka H, Ghaemi A, Verbavatz JM, Brusch L, Sbalzarini I, Kalaidzidis Y, Weigert R, Zerial M.
Meyer K, et al.
Cell Syst. 2017 Mar 22;4(3):277-290.e9. doi: 10.1016/j.cels.2017.02.008. Epub 2017 Mar 18.
Cell Syst. 2017.
PMID: 28330614
Free PMC article.
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