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Nanobody-targeted photodynamic therapy induces significant tumor regression of trastuzumab-resistant HER2-positive breast cancer, after a single treatment session.
Deken MM, Kijanka MM, Beltrán Hernández I, Slooter MD, de Bruijn HS, van Diest PJ, van Bergen En Henegouwen PMP, Lowik CWGM, Robinson DJ, Vahrmeijer AL, Oliveira S. Deken MM, et al. J Control Release. 2020 Jul 10;323:269-281. doi: 10.1016/j.jconrel.2020.04.030. Epub 2020 Apr 21. J Control Release. 2020. PMID: 32330574 Free PMC article.
EGFR targeted nanobody-photosensitizer conjugates for photodynamic therapy in a pre-clinical model of head and neck cancer.
van Driel PBAA, Boonstra MC, Slooter MD, Heukers R, Stammes MA, Snoeks TJA, de Bruijn HS, van Diest PJ, Vahrmeijer AL, van Bergen En Henegouwen PMP, van de Velde CJH, Löwik CWGM, Robinson DJ, Oliveira S. van Driel PBAA, et al. J Control Release. 2016 May 10;229:93-105. doi: 10.1016/j.jconrel.2016.03.014. Epub 2016 Mar 15. J Control Release. 2016. PMID: 26988602 Free PMC article.