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2016 | 3 |
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Dcp2: an mRNA decapping enzyme that adopts many different shapes and forms.
Curr Opin Struct Biol. 2019 Dec;59:115-123. doi: 10.1016/j.sbi.2019.07.009. Epub 2019 Aug 29.
Curr Opin Struct Biol. 2019.
PMID: 31473440
Free PMC article.
Review.
Changes in conformational equilibria regulate the activity of the Dcp2 decapping enzyme.
Wurm JP, Holdermann I, Overbeck JH, Mayer PHO, Sprangers R.
Wurm JP, et al.
Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6034-6039. doi: 10.1073/pnas.1704496114. Epub 2017 May 22.
Proc Natl Acad Sci U S A. 2017.
PMID: 28533364
Free PMC article.
Item in Clipboard
The Rrp4-exosome complex recruits and channels substrate RNA by a unique mechanism.
Cvetkovic MA, Wurm JP, Audin MJ, Schütz S, Sprangers R.
Cvetkovic MA, et al.
Nat Chem Biol. 2017 May;13(5):522-528. doi: 10.1038/nchembio.2328. Epub 2017 Mar 13.
Nat Chem Biol. 2017.
PMID: 28288106
Free PMC article.
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A general method for rapid and cost-efficient large-scale production of 5' capped RNA.
Fuchs AL, Neu A, Sprangers R.
Fuchs AL, et al.
RNA. 2016 Sep;22(9):1454-66. doi: 10.1261/rna.056614.116. Epub 2016 Jul 1.
RNA. 2016.
PMID: 27368341
Free PMC article.
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The S. pombe mRNA decapping complex recruits cofactors and an Edc1-like activator through a single dynamic surface.
Wurm JP, Overbeck J, Sprangers R.
Wurm JP, et al.
RNA. 2016 Sep;22(9):1360-72. doi: 10.1261/rna.057315.116. Epub 2016 Jun 28.
RNA. 2016.
PMID: 27354705
Free PMC article.
Item in Clipboard
The oligomeric architecture of the archaeal exosome is important for processive and efficient RNA degradation.
Audin MJ, Wurm JP, Cvetkovic MA, Sprangers R.
Audin MJ, et al.
Nucleic Acids Res. 2016 Apr 7;44(6):2962-73. doi: 10.1093/nar/gkw062. Epub 2016 Feb 2.
Nucleic Acids Res. 2016.
PMID: 26837575
Free PMC article.
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An excess of catalytically required motions inhibits the scavenger decapping enzyme.
Neu A, Neu U, Fuchs AL, Schlager B, Sprangers R.
Neu A, et al.
Nat Chem Biol. 2015 Sep;11(9):697-704. doi: 10.1038/nchembio.1866. Epub 2015 Aug 10.
Nat Chem Biol. 2015.
PMID: 26258763
Free PMC article.
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