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Year | Number of Results |
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2011 | 1 |
2013 | 3 |
2015 | 2 |
2016 | 1 |
2024 | 0 |
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Page 1
Design, synthesis, and biological evaluation of water-soluble amino acid prodrug conjugates derived from combretastatin, dihydronaphthalene, and benzosuberene-based parent vascular disrupting agents.
Bioorg Med Chem. 2016 Mar 1;24(5):938-956. doi: 10.1016/j.bmc.2016.01.007. Epub 2016 Jan 6.
Bioorg Med Chem. 2016.
PMID: 26852340
Free PMC article.
Structural interrogation of benzosuberene-based inhibitors of tubulin polymerization.
Herdman CA, Devkota L, Lin CM, Niu H, Strecker TE, Lopez R, Liu L, George CS, Tanpure RP, Hamel E, Chaplin DJ, Mason RP, Trawick ML, Pinney KG.
Herdman CA, et al.
Bioorg Med Chem. 2015 Dec 15;23(24):7497-520. doi: 10.1016/j.bmc.2015.10.012.
Bioorg Med Chem. 2015.
PMID: 26775540
Free PMC article.
Item in Clipboard
The vascular disrupting activity of OXi8006 in endothelial cells and its phosphate prodrug OXi8007 in breast tumor xenografts.
Strecker TE, Odutola SO, Lopez R, Cooper MS, Tidmore JK, Charlton-Sevcik AK, Li L, MacDonough MT, Hadimani MB, Ghatak A, Liu L, Chaplin DJ, Mason RP, Pinney KG, Trawick ML.
Strecker TE, et al.
Cancer Lett. 2015 Dec 1;369(1):229-41. doi: 10.1016/j.canlet.2015.08.021. Epub 2015 Sep 1.
Cancer Lett. 2015.
PMID: 26325604
Free PMC article.
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Synthesis of structurally diverse benzosuberene analogues and their biological evaluation as anti-cancer agents.
Tanpure RP, George CS, Strecker TE, Devkota L, Tidmore JK, Lin CM, Herdman CA, Macdonough MT, Sriram M, Chaplin DJ, Trawick ML, Pinney KG.
Tanpure RP, et al.
Bioorg Med Chem. 2013 Dec 15;21(24):8019-32. doi: 10.1016/j.bmc.2013.08.035. Epub 2013 Sep 4.
Bioorg Med Chem. 2013.
PMID: 24183586
Free PMC article.
Item in Clipboard
Synthesis of a 2-aryl-3-aroyl indole salt (OXi8007) resembling combretastatin A-4 with application as a vascular disrupting agent.
Hadimani MB, Macdonough MT, Ghatak A, Strecker TE, Lopez R, Sriram M, Nguyen BL, Hall JJ, Kessler RJ, Shirali AR, Liu L, Garner CM, Pettit GR, Hamel E, Chaplin DJ, Mason RP, Trawick ML, Pinney KG.
Hadimani MB, et al.
J Nat Prod. 2013 Sep 27;76(9):1668-78. doi: 10.1021/np400374w. Epub 2013 Sep 9.
J Nat Prod. 2013.
PMID: 24016002
Free PMC article.
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Synthesis and biological evaluation of indole-based, anti-cancer agents inspired by the vascular disrupting agent 2-(3'-hydroxy-4'-methoxyphenyl)-3-(3″,4″,5″-trimethoxybenzoyl)-6-methoxyindole (OXi8006).
Macdonough MT, Strecker TE, Hamel E, Hall JJ, Chaplin DJ, Trawick ML, Pinney KG.
Macdonough MT, et al.
Bioorg Med Chem. 2013 Nov 1;21(21):6831-43. doi: 10.1016/j.bmc.2013.07.028. Epub 2013 Jul 23.
Bioorg Med Chem. 2013.
PMID: 23993969
Free PMC article.
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Regioselective synthesis of water-soluble monophosphate derivatives of combretastatin A-1.
Tanpure RP, Nguyen BL, Strecker TE, Aguirre S, Sharma S, Chaplin DJ, Siim BG, Hamel E, Lippert JW, Pettit GR, Trawick ML, Pinney KG.
Tanpure RP, et al.
J Nat Prod. 2011 Jul 22;74(7):1568-74. doi: 10.1021/np200104t. Epub 2011 Jun 30.
J Nat Prod. 2011.
PMID: 21718055
Free PMC article.
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