337479/ERC_/European Research Council/International[Grants and Funding] - Search Results

Year	Number of Results
2015	2
2016	2
2017	4
2018	3
2019	2
2020	1
2022	2
2024	0

1

Systemic ASBT inactivation protects against liver damage in obstructive cholestasis in mice.

Kunst RF, de Waart DR, Wolters F, Duijst S, Vogels EW, Bolt I, Verheij J, Beuers U, Oude Elferink RPJ, van de Graaf SFJ. Kunst RF, et al. JHEP Rep. 2022 Aug 27;4(11):100573. doi: 10.1016/j.jhepr.2022.100573. eCollection 2022 Nov. JHEP Rep. 2022. PMID: 36160754 Free PMC article.

2

Differential and organ-specific functions of organic solute transporter α and β in experimental cholestasis.

van de Wiel SMW, Porteiro B, Belt SC, Vogels EWM, Bolt I, Vermeulen JLM, de Waart DR, Verheij J, Muncan V, Oude Elferink RPJ, van de Graaf SFJ. van de Wiel SMW, et al. JHEP Rep. 2022 Mar 5;4(5):100463. doi: 10.1016/j.jhepr.2022.100463. eCollection 2022 May. JHEP Rep. 2022. PMID: 35462858 Free PMC article.

3

Inhibition of Hepatic Bile Acid Uptake by Myrcludex B Promotes Glucagon-Like Peptide-1 Release and Reduces Obesity.

Donkers JM, Roscam Abbing RLP, van Weeghel M, Levels JHM, Boelen A, Schinkel AH, Oude Elferink RPJ, van de Graaf SFJ. Donkers JM, et al. Cell Mol Gastroenterol Hepatol. 2020;10(3):451-466. doi: 10.1016/j.jcmgh.2020.04.009. Epub 2020 Apr 21. Cell Mol Gastroenterol Hepatol. 2020. PMID: 32330730 Free PMC article.

4

Identification of FDA-approved drugs targeting the Farnesoid X Receptor.

van de Wiel SMW, Bijsmans ITGW, van Mil SWC, van de Graaf SFJ. van de Wiel SMW, et al. Sci Rep. 2019 Feb 18;9(1):2193. doi: 10.1038/s41598-019-38668-7. Sci Rep. 2019. PMID: 30778102 Free PMC article.

5

Developments in bile salt based therapies: A critical overview.

Donkers JM, Roscam Abbing RLP, van de Graaf SFJ. Donkers JM, et al. Biochem Pharmacol. 2019 Mar;161:1-13. doi: 10.1016/j.bcp.2018.12.018. Epub 2018 Dec 22. Biochem Pharmacol. 2019. PMID: 30582898 Free article. Review.

6

Intestinal Farnesoid X Receptor Activation by Pharmacologic Inhibition of the Organic Solute Transporter α-β.

van de Wiel SMW, de Waart DR, Oude Elferink RPJ, van de Graaf SFJ. van de Wiel SMW, et al. Cell Mol Gastroenterol Hepatol. 2017 Nov 28;5(3):223-237. doi: 10.1016/j.jcmgh.2017.11.011. eCollection 2018 Mar. Cell Mol Gastroenterol Hepatol. 2017. PMID: 29675448 Free PMC article.

7

Na⁺ -taurocholate cotransporting polypeptide inhibition has hepatoprotective effects in cholestasis in mice.

Slijepcevic D, Roscam Abbing RLP, Fuchs CD, Haazen LCM, Beuers U, Trauner M, Oude Elferink RPJ, van de Graaf SFJ. Slijepcevic D, et al. Hepatology. 2018 Sep;68(3):1057-1069. doi: 10.1002/hep.29888. Epub 2018 Apr 27. Hepatology. 2018. PMID: 29572910 Free PMC article.

8

Reduced hepatitis B and D viral entry using clinically applied drugs as novel inhibitors of the bile acid transporter NTCP.

Donkers JM, Zehnder B, van Westen GJP, Kwakkenbos MJ, IJzerman AP, Oude Elferink RPJ, Beuers U, Urban S, van de Graaf SFJ. Donkers JM, et al. Sci Rep. 2017 Nov 10;7(1):15307. doi: 10.1038/s41598-017-15338-0. Sci Rep. 2017. PMID: 29127322 Free PMC article.

9

Hepatic uptake of conjugated bile acids is mediated by both sodium taurocholate cotransporting polypeptide and organic anion transporting polypeptides and modulated by intestinal sensing of plasma bile acid levels in mice.

Slijepcevic D, Roscam Abbing RLP, Katafuchi T, Blank A, Donkers JM, van Hoppe S, de Waart DR, Tolenaars D, van der Meer JHM, Wildenberg M, Beuers U, Oude Elferink RPJ, Schinkel AH, van de Graaf SFJ. Slijepcevic D, et al. Hepatology. 2017 Nov;66(5):1631-1643. doi: 10.1002/hep.29251. Epub 2017 Sep 29. Hepatology. 2017. PMID: 28498614 Free PMC article.

10

N-Glycosylation of the Na+-Taurocholate Cotransporting Polypeptide (NTCP) Determines Its Trafficking and Stability and Is Required for Hepatitis B Virus Infection.

Appelman MD, Chakraborty A, Protzer U, McKeating JA, van de Graaf SF. Appelman MD, et al. PLoS One. 2017 Jan 26;12(1):e0170419. doi: 10.1371/journal.pone.0170419. eCollection 2017. PLoS One. 2017. PMID: 28125599 Free PMC article.

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